Impact of hypnosis during embryo transfer on the outcome of in vitro fertilization–embryo transfer: a case-control study
Received 2 March 2005; received in revised form 11 October 2005; accepted 11 October 2005. published online 27 March 2006.
Objective
To investigate whether hypnosis during ET contributes to successful IVF/ET outcome.
Design
Case-control clinical study.
Setting
Academic Fertility and IVF Unit, Soroka Medical Center, Beer-Sheva, Israel.
Patient(s)
Infertile couples undergoing IVF.
Intervention(s)
Ninety-eight IVF/ET cycles with hypnosis during the ET procedure were matched with 96 regular IVF/ET cycles.
Main Outcome Measures
Comparison of clinical pregnancy and implantation rates between the two groups.
Result(s)
We obtained 52 clinical pregnancies out of 98 cycles (53.1%) with an implantation rate of 28% among hypnosis IVF/ET cycles, and 29 out of 96 (30.2%) clinical pregnancies and an implantation rate of 14.4% in the control cycles. Our overall IVF program pregnancy rate for the same period was 32.1%. Logistic regression analysis was performed emphasizing the positive contribution of hypnosis to the IVF/ET conception rates.
Conclusion(s)
This study suggests that the use of hypnosis during ET may significantly improve the IVF/ET cycle outcome in terms of increased implantation and clinical pregnancy rates. Furthermore, it seems that the patients’ attitude to the treatment was more favorable.
aFertility and IVF Unit, Soroka University Medical Center, Beer-Sheva, Israel
bDepartment of Obstetrics and Gynecology, Soroka University Medical Center, Beer-Sheva, Israel
cDepartment of Epidemiology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Reprint requests: Eliahu Levitas, M.D., IVF Unit, Department of Obstetrics and Gynecology, Soroka University Medical Center, P.O. Box 151, Beer Sheva, 84101, Israel (FAX: 972-8-640-3057)
ABSTRACT