Expressions of steroid receptors and Ki67 in first-trimester decidua and chorionic villi exposed to levonorgestrel used for emergency contraception
Levonorgestrel (1.5 mg) is commonly used for emergency contraception to prevent an unwanted pregnancy after an unprotected intercourse. We found that postovulatory administration of 1.5 mg of levonorgestrel to women with a subsequent or existing early pregnancy did not affect the immunohistochemical expressions of estrogen receptors (ERα, ERβ), P receptors (PRB, PRA+B), androgen receptor (AR), or proliferation index Ki67 in the first-trimester decidua and chorionic villi.
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C.-X.M. has nothing to disclose. L.-N.C. has nothing to disclose. P.G.L.L.K. has nothing to disclose. L.Z. has nothing to disclose. H.-J.Z. has nothing to disclose. K.G.-D. has nothing to disclose.
Li-Nan Cheng and Kristina Gemzell-Danielsson contributed equally to the study.
Supported by Chinese Committee of Population and Family Planning (2004BA709B11) and Swedish Medical Research Council (K2007-54X-14212-06-3) and Stockholm City County, Karolinska Institutet (ALF).
PII: S0015-0282(08)01165-5
doi:10.1016/j.fertnstert.2008.05.058
© 2009 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

