Fertility and Sterility
Volume 94, Issue 7 , Pages 2898-2901, December 2010

Obesity and age affect male fertility potential

  • Uwe Paasch, M.D., Ph.D.

      Affiliations

    • Department of Dermatology, Training Center of the European Academy of Andrology, University of Leipzig, Leipzig, Germany
    • Corresponding Author InformationReprint requests: Uwe Paasch, M.D., Ph.D., Department of Dermatology, Training Center of the European Academy of Andrology, University of Leipzig, Philipp-Rosenthal-Strasse 23, D 04103 Leipzig, Germany (FAX: 49-341-9718749).
    • ,
  • Sonja Grunewald, M.D., Ph.D.

      Affiliations

    • Department of Dermatology, Training Center of the European Academy of Andrology, University of Leipzig, Leipzig, Germany
    • ,
  • Juergen Kratzsch, M.D., Ph.D.

      Affiliations

    • Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig, Germany
    • ,
  • Hans-Juergen Glander, M.D., Ph.D.

      Affiliations

    • Department of Dermatology, Training Center of the European Academy of Andrology, University of Leipzig, Leipzig, Germany

Received 16 February 2010; received in revised form 8 June 2010; accepted 16 June 2010. published online 29 July 2010.

A case–cohort study of 2,157 patients, aged 17–67 years was performed to assess the impact of body mass index and age on male fertility. Using a multiple regression analysis across the total cohort, only age correlated significantly with all spermiogram parameters and serum hormones, but in patients aged 20–30 years (n = 617) the total sperm count was significantly negatively correlated with body mass index.

Key Words: Body mass index, age, sperm counts, testosterone, FSH, inhibin-B, LH

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 U.P. has nothing to disclose. S.G. has nothing to disclose. J.K. has nothing to disclose. H-J.G. has nothing to disclose.

 H-J.G. received a funding grant from the German Research Council (GL 199/4-4). U.P. and J.K. received funding from the German Research Council (PA 834.7-1 KFO152.8A 152/8).

PII: S0015-0282(10)01000-9

doi:10.1016/j.fertnstert.2010.06.047

Fertility and Sterility
Volume 94, Issue 7 , Pages 2898-2901, December 2010

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