Fertility and Sterility
Volume 74, Issue 5 , Pages 877-880 , November 2000

Predictors of treatment failure for ectopic pregnancy treated with single-dose methotrexate

Presented at the joint meeting of the American Society for Reproductive Medicine and the Canadian Fertility and Andrology Society, which was held in Toronto, Ontario, Canada, September 25–30, 1999.

  • Afaf Tawfiq, M.D.

      Affiliations

    • Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • Abdul-Fattah Agameya, M.D.

      Affiliations

    • Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    • ,
  • Paul Claman, M.D.

      Affiliations

    • Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    • Corresponding Author InformationReprint requests: Paul Claman, M.D., Suite 505, 737 Carling Avenue, Ottawa, Ontario, Canada K1Y4E9 (FAX: 613-761-4678;

Received 4 February 2000 ,Accepted 31 May 2000.

References 

  1. Lau S, Tulandi T. Conservative medical and surgical management of interstitial ectopic pregnancy. Fertil Steril. 1999;72:207–215
  2. Ory SJ, Villanueva AL, Sand PK, Tamura RK. Conservative treatment of ectopic pregnancy with methotrexate. Am J Obstet Gynecol. 1986;154:1299–1306
  3. Stovall TG, Ling FW. Single dose methotrexate (an expanded clinical trial). Am J Obstet Gynecol. 1993;168:1759–1765
  4. Glock JL, Johnson JV, Brumsted JR. Efficacy and safety of single-dose systemic methotrexate in the treatment of ectopic pregnanacy. Fertil Steril. 1994;62:716–721
  5. Stika CS, Anderson L, Frederiksen MC. Single-dose methotrexate for the treatment of ectopic pregnancy (Northwestern Memorial Hospital three-year experience). Am J Obstet Gynecol. 1996;174:1840–1848
  6. Perkins SL, Al-Ramahi M, Claman P. Comparison of serum progesterone as an indicator of pregnancy nonviabilty in spontaneously pregnant emergency room and infertility clinic patient populations. Fertil Steril. 2000;73:499–504
  7. Corsan GH, Karacan M, Qasim S, Bohrer MK, Ransom MX, Kemmann E. Identification of hormonal parameters for successful systemic single-dose methotrexate therapy in ectopic pregnancy. Hum Reprod. 1995;10:2719–2722
  8. Kooi S, Kock HC. A review of the literature on non surgical treatment in tubal pregnancies. Obstet Gynecol Surv. 1992;47:739–749
  9. ACOG Practice Bulletin. Medical management of tubal pregnancy. Clinical Management Guidelines number 3, December 1998.
  10. Speroff L, Glass R, Kase N. Ectopic pregnancy. In: Clinical Gynecologic Endocrinology and Infertility. 6th edition, Lippincott Williams & Wilkins, Baltimore, MD. 1999:1159.
  11. Lipscomb G, McCord M, Stovall T, Huff G, Portera S G, Ling FW. Predictors of success of methotrexate treatment in women with tubal ectopic pregnancies. N Engl J Med 1999;341:1974–8.

PII: S0015-0282(00)01547-8

Fertility and Sterility
Volume 74, Issue 5 , Pages 877-880 , November 2000

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