Fertility and Sterility
Volume 74, Issue 5 , Pages 909-915 , November 2000

Y chromosome analysis of infertile men and their sons conceived through intracytoplasmic sperm injection: vertical transmission of deletions and rarity of de novo deletions

  • David S Cram, Ph.D. (a,b)

      Affiliations

    • Monash IVF, Melbourne, Victoria, Australia
    • Monash Institute of Reproduction and Development, Monash University, Clayton, Victoria, Australia
    • The contributions of the two authors was deemed equal.
    • Corresponding Author InformationReprint requests: David Cram, Ph.D., Monash Institute of Reproduction and Development, 27-31 Wright St., Clayton, Victoria, Australia, 3168 (FAX: 61-3-95947311 )
    • ,
  • Kun Ma, Ph.D. (c)

      Affiliations

    • Division of Endocrinology, Metabolism, and Molecular Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, USA
    • The contributions of the two authors was deemed equal.
    • ,
  • Shalender Bhasin, M.D. (c)

      Affiliations

    • Division of Endocrinology, Metabolism, and Molecular Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, USA
    • ,
  • Jose Ariasc

      Affiliations

    • Division of Endocrinology, Metabolism, and Molecular Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, USA
    • ,
  • Marintan Pandjaitanc

      Affiliations

    • Division of Endocrinology, Metabolism, and Molecular Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, USA
    • ,
  • Brendan Chu
    • ,
  • M.S.bPam Audrins, B.A. (a)

      Affiliations

    • Monash Institute of Reproduction and Development, Monash University, Clayton, Victoria, Australia
    • Monash IVF, Melbourne, Victoria, Australia
    • Monash IVF, Melbourne, Victoria, Australia
    • ,
  • Doug Saunders, M.D. (d)

      Affiliations

    • Department of Obstetrics and Gynecology, University of Sydney at Royal North Shore Hospital, Sydney, New South Wales, Australia
    • ,
  • Frank Quinn, M.D. (d)

      Affiliations

    • Department of Obstetrics and Gynecology, University of Sydney at Royal North Shore Hospital, Sydney, New South Wales, Australia
    • ,
  • David deKretser, M.D. (b)

      Affiliations

    • Monash Institute of Reproduction and Development, Monash University, Clayton, Victoria, Australia
    • ,
  • Robert McLachlan (M.D.a,e)

      Affiliations

    • Monash IVF, Melbourne, Victoria, Australia
    • Prince Henry’s Institute of Medical Research, Melbourne, Victoria, Australia

Received 10 January 2000 ,Accepted 17 May 2000.

References 

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  3. Reijo R, Lee T-Y, Salo P, Alagappan R, Brown LG, Rosenburg M, et al.  Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein. Nat Genet. 1995;10:383–393
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☆ This research was funded by a grant from Monash IVF Propriety Limited and RCMI grants P20RR11145-01 and G12RR03026.

PII: S0015-0282(00)01568-5

Fertility and Sterility
Volume 74, Issue 5 , Pages 909-915 , November 2000

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