Fertility and Sterility
Volume 75, Issue 2 , Pages 342-347 , February 2001

Intracytoplasmic sperm injection increased fertilization and good-quality embryo formation in patients with non–male factor indications for in vitro fertilization: a prospective randomized study1

  • Firouz Khamsi (M.B., Ch.B.)

      Affiliations

    • Toronto Fertility Sterility Institute, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests: Firouz Khamsi, M.D., Toronto Fertility Sterility Institute, 66 Avenue Road, Toronto, Ontario, Canada, M5R 3N8 (FAX: 416-963-9931 )
    • ,
  • Yalcin Yavas, Ph.D.

      Affiliations

    • Toronto Fertility Sterility Institute, Toronto, Ontario, Canada
    • ,
  • Sylvie Roberge, Ph.D.

      Affiliations

    • Toronto Fertility Sterility Institute, Toronto, Ontario, Canada
    • ,
  • Jeremy C Wong, M.D.

      Affiliations

    • Toronto Fertility Sterility Institute, Toronto, Ontario, Canada
    • ,
  • Iara C Lacanna, M.D.

      Affiliations

    • Toronto Fertility Sterility Institute, Toronto, Ontario, Canada
    • ,
  • Maxine Endman, Ph.D.

      Affiliations

    • Toronto Fertility Sterility Institute, Toronto, Ontario, Canada

Received 7 October 1999 ,Accepted 31 July 2000.

References 

  1. Khamsi F, Lacanna I, Endman M, Wong J. Recent advances in assisted reproductive technologies. Endocrine. 1998;9:15–25
  2. Ziebe S, Andersen AN, Andersen AG, Mikkelsen AL, Lindenberg S. Results of intracytoplasmic sperm injection in relation to indication. Acta Obstet Gynecol Scand. 1997;76:335–339
  3. Aboulghar MA, Mansour RT, Serour GI, Sattar MA, Amin YM. Intracytoplasmic sperm injection and conventional in vitro fertilization for sibling oocytes in cases of unexplained infertility and borderline semen. J Assist Reprod Genet. 1996;13:38–42
  4. Ruiz A, Remohi J, Minguez Y, Guanes PP, Simon C, Pellicer A. The role of in vitro fertilization and intracytoplasmic sperm injection in couples with unexplained infertility after failed intrauterine insemination. Fertil Steril. 1997;68:171–173
  5. WHO laboratory manual for examination of human semen and sperm. 3rd ed. New York: Cambridge University Press, 1992:44.
  6. Khamsi F, Roberge S, Lacanna IC, Wong J, Yavas Y. Effect of granulosa cells, cumulus cells, and oocyte density on in vitro fertilization in women. Endocrine. 1999;10:161–166
  7. SAS/STAT User’s Guide, Release 6.03 ed. Cary (NC): SAS, Inc., 1996.
  8. Jun JH, Lim CK, Kim JW, Son IP, Koong MK, Song IO, et al. Comparison of fertilization and embryonic development between conventional insemination and ICSI treatment in the sibling oocytes of non-male factor infertility [abstract]. In: Program supplement of the Annual Meeting of American Society for Reproductive Medicine. 1999;72(Suppl 1):S6.
  9. Staessen C, Camus M, Clasen K, DeVos A, Van Steirteghem A. Conventional in vitro fertilization versus intracytoplasmic sperm injection in sibling oocytes from couples with tubal infertility and normozoospermic semen. Hum Reprod. 1999;10:2474–2479
  10. Margalioth EJ, Navot D, Laufer N, Lewin A, Rabinowitz R, Schenker JG. Correlation between the zona-free hamster egg sperm penetration assay and human in vitro fertilization. Fertil Steril. 1986;45:665–670
  11. Chen SH, Wallach EE. Five decades of progress in management of the infertile couple. Fertil Steril. 1994;62:665–685

PII: S0015-0282(00)01674-5

Fertility and Sterility
Volume 75, Issue 2 , Pages 342-347 , February 2001

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