Fertility and Sterility
Volume 75, Issue 2 , Pages 348-353 , February 2001

The spindle observation and its relationship with fertilization after intracytoplasmic sperm injection in living human oocytes

Presented at the 55th Conjoint Annual Meeting of the American Society for Reproductive Medicine and the Canadian Fertility and Andrology Society, Toronto, Ontario, Canada, September 25–30, 1999.

  • Wei-Hua Wang, Ph.D. (a)

      Affiliations

    • Division of Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University School of Medicine, Providence, Rhode Island, USA
    • ,
  • Li Meng, Ph.D. (a)

      Affiliations

    • Division of Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University School of Medicine, Providence, Rhode Island, USA
    • ,
  • Rickard J Hackett (M.Sc.,a)

      Affiliations

    • Division of Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University School of Medicine, Providence, Rhode Island, USA
    • ,
  • Rudolf Odenbourg, Ph.D. (b)

      Affiliations

    • Division of Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, New England Medical Center, Providence, Rhode Island, USA
    • ,
  • David L Keefe (M.D.a,b,c)

      Affiliations

    • Division of Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University School of Medicine, Providence, Rhode Island, USA
    • Division of Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, New England Medical Center, Providence, Rhode Island, USA
    • Marine Biological Laboratory, Woods Hole Massachusetts, USA

Received 25 April 2000 ,Accepted 9 August 2000.

References 

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  10. Benadiva CA, Kligman I, Munne S. Aneuploidy 16 in human embryos increases significantly with maternal age. Fertil Steril. 1996;66:248–255
  11. Plachot M. Aneuploidy rates in blastomeres. In:  Kempers RD,  Cohen J,  Haney AF,  Younger JB editor. Fertility and reproductive medicine. Amsterdam: Elsevier Science; 1998;p. 711–720
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  13. Battaglia DG, Goodwin P, Klein NA, Soules MR. Influence of maternal age on meiotic spindle in oocytes from naturally cycling women. Hum Reprod. 1996;11:2217–2222
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  17. Waterman-Storer CM. Microtubules and microscopes (how the development of light microscopic imaging technologies has contributed to discoveries about microtubule dynamics in living cells). Mol Biol Cell. 1998;9:3263–3271
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  19. Silva CP, Kommineni K, Oldenbourg R, Keefe DL. The first polar body does not predict accurately the location of the metaphase 2 meiotic spindle in mammalian oocytes. Fertil Steril. 1999;71:719–721
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☆ Supported by National Institutes of Health K08 1099 and by the Women and Infants Hospital Faculty Research Fund.

PII: S0015-0282(00)01692-7

Fertility and Sterility
Volume 75, Issue 2 , Pages 348-353 , February 2001

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