Fertility and Sterility
Volume 75, Issue 2 , Pages 337-341 , February 2001

Progesterone supplementation during early gestation after in vitro fertilization has no effect on the delivery rate

  • Kirsten Louise Tryde Schmidt, M.D.

      Affiliations

    • The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    • ,
  • Søren Ziebe (M.Sc.)

      Affiliations

    • The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    • ,
  • Biljana Popovic, M.D.

      Affiliations

    • The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    • ,
  • Anette Lindhard, M.D.

      Affiliations

    • The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    • ,
  • Anne Loft, M.D.

      Affiliations

    • The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    • ,
  • Anders Nyboe Andersen, M.D. (D.Sci.)

      Affiliations

    • The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    • Corresponding Author InformationReprint requests: Anders Nyboe Andersen, M.D. D.Sci. The Fertility Clinic 4071, The Juliane Marie Center, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark (FAX: 45-35-45-49-46 )

Received 2 February 2000 ,Revised 23 August 2000 ,Accepted 23 August 2000.

References 

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  2. Smitz J, Devroey P, Braeckmans P, Camus M, Khan I, Staessen C, et al.  Management of failed cycles in an IVF/GIFT programme with the combination of a GnRH analogue and HMG. Hum Reprod. 1987;2:309–314
  3. Smitz J, Devroey P, Camus M, Deschacht J, Khan I, Staessen C, et al.  The luteal phase and early pregnancy after combined GnRH-agonist/HMG treatment for superovulation in IVF or GIFT. Hum Reprod. 1988;3:585–590
  4. Bourgain C, Smitz J, Camus M, Erard P, Devroey P, Van Steirteghem AC, et al.  Human endometrial maturation is markedly improved after luteal supplementation of gonadotrophin-releasing hormone analogue/human menopausal gonadotrophin stimulated cycles. Hum Reprod. 1994;9:32–40
  5. Nilsson L, Wikland M, Hamberger L. Assisterad befruktning–IVF. In: Svensk Förenings för Obsterik och Gynekologi Arbets- och Referensgrupp för Ofrivillig barnlöshet. Rapport nr: 37. SFOG: Stockholm 1998;114.
  6. Smitz J, Devroey P, Faguer B, Bourgain C, Camus M, Van Steirteghem AC. A prospective randomized comparison of intramuscular or intravaginal natural progesterone as a luteal phase and early pregnancy supplement. Hum Reprod. 1992;7:168–175
  7. Bourgain C, Devroey P, Van Waesberghe L, Smitz J, Van Steirteghem AC. Effects of natural progesterone on the morphology of the endometrium in patients with primary ovarian failure. Hum Reprod. 1990;5:537–543
  8. Polson DW, Rogers PAW, Krapez JA, Leeton JF. Vaginal progesterone as luteal phase support in an IVF/GIFT programme. Eur J Obstet Gynecol Reprod Biol. 1992;46:35–38
  9. Miles RA, Paulson RJ, Lobo RA, Press MF, Dahmoush MD, Sauer MV. Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes (a comparative study). Fertil Steril. 1994;62:485–490
  10. Mochtar MH, Hogerzeil HV, Mol BWJ. Progesterone alone versus progesterone combined with HCG as luteal support in GnRHa/HMG induced IVF cycles (a randomised clinical trial). Hum Reprod. 1996;11:1602–1605
  11. Van Steirteghem AC, Smitz J, Camus M, Van Waesberghe L, Deschacht J, Khan I, et al.  The luteal phase after in-vitro fertilization and related procedures. Hum Reprod. 1988;3:161–164
  12. Sohn SH, Penzias AS, Emmi AM, Dubey AK, Layman LC, Reindollar RH, et al.  Administration of progesterone before oocyte retrieval negatively affects the implantation rate. Fertil Steril. 1999;17:11–14
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  17. Spandorfer SD, Schattman G, Liu H-C, Stephens A, Rosenwaks Z. The lutealplacental shift (LP): when does it occur? [abstract]. In: Abstracts of the Scientific Oral and Poster Sessions of IFFS ‘98 16th World Congress on Fertility and Sterility and 54th Annual Meeting of the American Society for Reproductive Medicine. 1998:148.

PII: S0015-0282(00)01709-X

Fertility and Sterility
Volume 75, Issue 2 , Pages 337-341 , February 2001

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