Fertility and Sterility
Volume 75, Issue 4 , Pages 661-668 , April 2001

Effect of the total motile sperm count on the efficacy and cost-effectiveness of intrauterine insemination and in vitro fertilization

  • Bradley J Van Voorhis, M.D.

      Affiliations

    • Department of Obstetrics & Gynecology, University of Iowa College of Medicine Iowa City, Iowa USA
    • Corresponding Author InformationReprint requests: Bradley J. Van Voorhis, M.D., Department of Obstetrics & Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242-1080 (FAX: 319-353-6659 )
    • ,
  • Mitchell Barnett (R.Ph., M.Sc.)

      Affiliations

    • Department of Internal Medicine, University of Iowa College of Medicine Iowa City, Iowa USA
    • ,
  • Amy E.T Sparks, Ph.D.

      Affiliations

    • Department of Obstetrics & Gynecology, University of Iowa College of Medicine Iowa City, Iowa USA
    • ,
  • Craig H Syrop, M.D.

      Affiliations

    • Department of Obstetrics & Gynecology, University of Iowa College of Medicine Iowa City, Iowa USA
    • ,
  • Gary Rosenthal, M.D.

      Affiliations

    • Department of Internal Medicine, University of Iowa College of Medicine Iowa City, Iowa USA
    • ,
  • Jeffrey Dawson (Sc.D.)

      Affiliations

    • Department of Preventive Medicine, University of Iowa College of Medicine Iowa City, Iowa USA

Received 31 March 2000 ,Revised 2 October 2000 ,Accepted 2 October 2000.

References 

  1. Guzick DS, Carson SA, Coutifaris C, Overstreet JW, Factor-Litvak P, Steinkampf MP, et al.  Efficacy of superovulation and intrauterine insemination in the treatment of infertility. N Engl J Med. 1999;340:177–183
  2. Hughes EG. The effectiveness of ovulation induction and intrauterine insemination in the treatment of persistent infertility (meta-analysis). Hum Reprod. 1997;12:1865–1872
  3. Goverde AJ, McDonnell J, Vermeiden JPW, Schats R, Rutten FFH, Schoemaker J. Intrauterine insemination or in-vitro fertilization in idiopathic subfertility and male subfertility (a randomized trial and cost-effectiveness analysis). Lancet. 2000;355:12–18
  4. Cohlen BJ, te Velde ER, van Kooij RJ, Looman CWN, Habbema JDF. Controlled ovarian hyperstimulation and intrauterine insemination for treating male subfertility (a controlled study). Hum Reprod. 1998;13:1553–1558
  5. Ayala C, Steinberger E, Smith DP. The influence of semen analysis parameters on the fertility potential of infertile couples. J Androl. 1996;17:718–725
  6. Glazener CMA, Kelly NJ, Weir MJ, David JS, Cornes JS, Hull MG. The diagnosis of male infertility-prospective time-specific study of conception rates related to seminal analyses and post-coital sperm-mucus penetration and survival in otherwise unexplained infertility. Hum Reprod. 1987;2:665–671
  7. Makler A. The improved ten-micrometer chamber for rapid sperm count and motility evaluation. Fertil Steril. 1980;33:337–338
  8. Syrop CH, Dawson JD, Husman KJ, Sparks AET, Van Voorhis BJ. Ovarian volume may predict assisted reproductive outcomes better than follicle stimulating hormone concentration on day 3. Hum Reprod. 1999;14:1752–1756
  9. Van Voorhis BJ, Syrop CH, Allen BD, Sparks AET, Stovall DW. The efficacy and cost effectiveness of embryo cryopreservation compared with other assisted reproductive techniques. Fertil Steril. 1995;64:647–650
  10. Van Voorhis BJ, Sparks A, Allen B, Stovall D, Syrop C, Chapler FK. Cost-effectiveness of infertility treatment (a cohort study). Fertil Steril. 1997;67:830–836
  11. Van Voorhis BJ, Stovall DW, Allen BA, Syrop CH. Cost-effective treatment of the infertile couple. Fertil Steril. 1998;70:995–1005
  12. Society for Assisted Reproductive Technology and Centers for Disease Control and Prevention. 1997 Assisted Reproductive Technology Success Rates National Summary and Fertility Clinic Reports. Available at: http//www.cdc.giv/nccdphp/drh/art97/.
  13. ESHRE Capri Workshop . Guidelines to the prevalence, diagnosis, treatment and management of infertility, 1996. Hum Reprod. 1996;11:1775–1807
  14. Peterson CM, Poulson AM, Hatasaka HH, Carrell DT, Jones KP, Urry RL. Ovulation induction with gonadotropins and intrauterine insemination compared with in vitro fertilization and no therapy (a prospective, nonrandomized, cohort study and meta-analysis). Fertil Steril. 1994;63:535–544
  15. Ombelet W, Vandeput H, Van de Putte G, Cox A, Janssen M, Jacobs P, et al.  Intrauterine insemination after ovarian stimulation with clomiphene citrate (predictive potential of inseminating motile count and sperm morphology). Hum Reprod. 1997;12:1458–1463
  16. Berg U, Brucker C, Berg FD. Effect of motile sperm count after swim-up on outcome of intrauterine insemination. Fertil Steril. 1997;67:747–750
  17. Ash AS, Schwartz M. Evaluating the performance of risk-adjustment methods (dichotomous measures). In:  Iezzoni LI editors. Risk adjustment for measuring health care outcomes. Chicago, IL: Health Administration Press; 1994;p. 313–346
  18. Horvath PM, Bohrer M, Shelden RM, Kemmann E. The relationship of sperm parameters to cycle fecundity in superovulated women undergoing intrauterine insemination. Fertil Steril. 1989;52:288–294
  19. Dickey RP, Pyrzak R, Lu PY, Taylor SN, Rye PH. Comparison of the sperm quality necessary for successful intrauterine insemination with World Health Organization threshold values for normal sperm. Fertil Steril. 1999;71:684–689
  20. Campana A, Sakkas D, Stalberg A, Bianchi PG, Comte I, Pache T, et al.  Intrauterine insemination (evaluation of the results according to the women’s age, sperm quality, total sperm count per insemination and life table analysis). Hum Reprod. 1996;11:732–736
  21. Evers JLH, de Haas HW, Land JA, Dumoulin JCM, Dunselman GAJ. Treatment-independent pregnancy rate in patients with severe reproductive disorders. Hum Reprod. 1998;13:1206–1209
  22. Collins JA, Burrows EA, Willan AR. The prognosis for live birth among untreated infertile couples. Fertil Steril. 1995;64:22–28
  23. Adamson GD. A 36-year-old woman with endometriosis, pelvic pain, and infertility. JAMA. 1999;282:2347–2354
  24. Tielemans E, Heederik D, Burdorf A, Loomis D, Habbema DF. Intraindividual variability and redundancy of semen parameters. Epidemiology. 1997;8:99–103
  25. te Velde ER, van Kooy RJ, Waterreus JJH. Intrauterine insemination of washed husband’s spermatozoa (a controlled study). Fertil Steril. 1989;51:182–185
  26. Ho PC, Poon IML, Chan SYW, Wang C. Intrauterine insemination is not useful in oligoasthenospermia. Fertil Steril. 1989;51:682–684
  27. Arici A, Byrd W, Bradshaw K, Kutteh WH, Marshburn P, Carr BR. Evaluation of clomiphene citrate and human chorionic gonadotropin treatment (a prospective, randomized, crossover study during intrauterine insemination cycles). Fertil Steril. 1994;61:314–318
  28. Brasch JG, Rawlins R, Tarchala S, Radwanska E. The relationship between total motile sperm count and the success of intrauterine insemination. Fertil Steril. 1994;62:150–154
  29. Kirby CA, Warnes GM, Flaherty SP, Matthews CD, Godfrey BM. A prospective trial of intrauterine insemination of motile spermatozoa versus timed intercourse. Fertil Steril. 1991;56:102–107
  30. Cruz RI, Kemmann E, Brandeis VT, Becker KA, Beck M, Beardsley L, et al.  A prospective study of intrauterine insemination of processed sperm from men with oligoasthenospermia in superovulated women. Fertil Steril. 1986;46:673–677

PII: S0015-0282(00)01783-0

Fertility and Sterility
Volume 75, Issue 4 , Pages 661-668 , April 2001

Article Tools