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Fertility and Sterility
Volume 76, Issue 4
, Pages 730-735
, October 2001
Influence of insulin and testosterone on adrenocortical steroidogenesis in vitro: preliminary studies
References
- . Prevalence of the polycystic ovarian syndrome in unselected Black and White women of the southeastern United States (a prospective study). J Clin Endocrinol Metab. 1998;83:3078–3082
- . Insulin resistance and the polycystic ovary syndrome (mechanism and implications for pathogenesis). Endocr Rev. 1997;18:774–800
- . Does ethnicity influence the prevalence of adrenal hyperandrogenism and insulin resistance in polycystic ovary syndrome?. Am J Obstet Gynecol. 1992;167:1807–1812
- . Adrenal androgen excess in hyperandrogenism (relationship of age and body mass). Fertil Steril. 1999;71:671–674
- . The effects of prolonged hypertestosteronemia on adrenocortical biosynthesis in oophorectomized women. J Clin Endocrinol Metab. 1991;72:1025–1030
- . Sex differences in the twenty four hour plasma concentration of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHAS) and the DHEA/DHAS ratio in normal adults. J Clin Endocrinol Metab. 1980;51:330–333
- . The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans. J Clin Endocrinol Metab. 1987;64:180–184
- . Effect of acute physiological elevations of insulin on circulating androgen levels in nonobese women. J Clin Endocrinol Metab. 1991;72:883–887
- . Suppression of circulating delta4-androstenedione and dehydroepiandrosterone sulfate during oral glucose tolerance test in normal females. J Clin Endocrinol Metab. 1991;73:781–784
- . Divergent correlations of circulating dehydroepiandrosterone sulfate and testosterone with insulin levels and insulin receptor binding. J Clin Endocrinol Metab. 1988;66:1329–1331
-
Insulin resistance in patients with polycystic ovaries (its relationship to body weight and androgen levels).
Acta Endocrinol. 1983;104:110–116
-
.
Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with polycystic ovary syndrome.
J Clin Invest. 1989;82:23–29
- . Androgen responses to acutely increased endogenous insulin levels in hyperandrogenic and normal cycling women. Fertil Steril. 1991;55:486–491
- . Insulin infusion acutely augments ovarian androgen production in normal women. Fertil Steril. 1990;54:788–792
- . No acute effect of physiological insulin increase on dehydroepiandrosterone sulfate in women with obesity and/or polycystic ovarian disease. Fertil Steril. 1991;56:1179–1182
- . Induction of steroidogenic enzyme genes by insulin and IFG-I in cultured adult human adrenocortical cells and resultant changes in the dehydroepiandrosterone/cortisol synthesis ratio. Steroids. 1997;62:258–265
- . Permissive effect of insulin on the adenosine 3′,5′-monophosphate-dependent up-regulation of low density lipoprotein receptors and the stimulation of steroid release in bovine adrenal cortical cells. Endocrinology. 1984;122:2518–2526
- . Mechanisms of insulin inhibition of ACTH-stimulated steroid secretion by cultured bovine adrenocortical cells. J Steroid Biochem Mol Biol. 1989;41:11–20
- . Regulation of the activities of 17-hydroxylase and 17,20-desmolase in the human adrenal cortex (kinetic analysis and inhibition by endogenous steroids). J Clin Endocrinol Metab. 1986;63:613–618
- . Steroid inhibitory effects upon human adrenal 3β-hydroxysteroid dehydrogenase activity. J Clin Endocrinol Metab. 1986;62:413–418
-
.
Physiologic testosterone (T) augments dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) secretion in human adrenocortical reticularis cells in vitro.
[abstract no. 388]
J Soc Gynecol Invest. 1997;4:176A
- . Impact of architectural disruption on adrenocortical steroidogenesis. J Clin Endocrinol Metab. 1999;84:1017–1021
- . Culturing steroidogenic cells. Method Enzymol. 1991;206:371–380
-
Hines GA, Azziz R. Relation of adrenal zonal mass and steroid production in vitro with human aging [abstract no. 121]. Tenth International Congress on Hormonal Steroids, Québec, Canada, June 17–21, 1998.
- . Intra-adrenal factors are not involved in the differential control of cortisol and adrenal androgens in human adrenals. Eur J Endocrinol. 1998;138:567–573
- . Age changes and sex differences in serum dehydroepiandrosterone sulfate concentration during adulthood. J Clin Endocrinol Metab. 1984;59:551–555
-
.
Effects of gonadal androgens and oestrogens on adrenal androgen levels.
Clin Endocrinol. 1995;43:415–421
- . Chronic hyperinsulinemia and the adrenal androgen response to acute corticotropin-(1-24) stimulation in hyperandrogenic women. Am J Obstet Gynecol. 1995;172:1251–1256
- . Adrenocortical secretion of dehydroepiandrosterone in healthy women (highly variable response to ACTH). J Clin Endocrinol Metab. 2001;86:2513–2517
- . Regulation of the acute production of steroids in steroidogenic cells. Endocr Rev. 1996;17:221–244
-
.
Steroid hormone biosynthesis in the adrenal cortex and its regulation by adrenocorticotropin.
In:
DeGroot LR editors. Endocrinology. 2nd ed. Philadelphia: W.B. Saunders; 1989;p. 1543–1556
- . Regulation of adrenal cell-differentiated functions by growth factors. Horm Res. 1994;42:39–43
- . Peptide growth factors and the adrenal cortex. Microsc Res Tech. 1997;36:558–568
-
.
Physiological and pathological effects of steroids on the function of the adrenal cortex.
J Steroid Biochem Mol Biol. 1987;27:1161–1171
- . Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocr Rev. 1998;19:101–143
☆ Supported in part by grant RO1-HD29364 from the National Institutes of Health, Bethesda, Maryland (R.A.).
PII: S0015-0282(01)02014-3
© 2001 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
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Fertility and Sterility
Volume 76, Issue 4
, Pages 730-735
, October 2001

