Fertility and Sterility
Volume 78, Issue 1 , Pages 58-62, July 2002

Hereditary thrombophilias are not associated with a decreased live birth rate in women with recurrent miscarriage

  • Howard Carp, B.S. (M.B., F.R.C.O.G.)

      Affiliations

    • Corresponding Author InformationReprint requests: Howard Carp, M.B., B.S., F.R.C.O.G., Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, 52621, Israel (FAX: 972-9-9574779)
    • Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel
    • Department of Embryology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    • ,
  • Mordechai Dolitzky, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel
    • ,
  • Ilan Tur-Kaspa, M.D.

      Affiliations

    • IVF Unit, Barzilai Medical Center, Ashkelon, Israel
    • ,
  • Aida Inbal, M.D.

      Affiliations

    • Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Israel

Received 23 October 2001; received in revised form 26 December 2001; accepted 26 December 2001.

Abstract 

Objective: To assesses the live birth rate without treatment in women with hereditary thrombophilia who have recurrent miscarriage and women without thrombophilia who have recurrent miscarriage.

Design: Prospective observational study.

Setting: Tertiary referral unit in university hospital.

Patient(s): One hundred twenty women with thrombophilia and 65 women without thrombophilia.

Main Outcome Measure(s): Number of live births or repeated miscarriages.

Results: Of the 185 patients, 44 with thrombophilia and 26 without thrombophilia have conceived. Nineteen of the 44 pregnancies (43.2%) in thrombophilia patients have terminated in live births, compared with 8 of 26 pregnancies (30.8%) in patients without thrombophilia. This difference is not statistically significant.

Conclusions: Hereditary thrombophilia did not seem to affect the live birth rate in women with recurrent miscarriage.

Keywords:  Habitual abortion, recurrent pregnancy loss, thrombophilia, hypercoagulability

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0015-0282(02)03152-7

Fertility and Sterility
Volume 78, Issue 1 , Pages 58-62, July 2002

Article Tools