Fertility and Sterility
Volume 79, Issue 1 , Pages 112-119 , January 2003

The Ontario Uterine Fibroid Embolization Trial. Part 1. Baseline patient characteristics, fibroid burden, and impact on life

  • Gaylene Pron, Ph.D.

      Affiliations

    • Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    • Center for Research in Women’s Health, Sunnybrook and Women’s College Health Sciences Center, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests: Gaylene Pron, Ph.D., Department of Public Health Sciences, Faculty of Medicine, University of Toronto, 100 College St., Room 513, Banting Building, Toronto, Ontario M5G 1L5, Canada (FAX: 416-971-2240).
    • ,
  • Marsha Cohen, M.D.

      Affiliations

    • Center for Research in Women’s Health, Sunnybrook and Women’s College Health Sciences Center, Toronto, Ontario, Canada
    • ,
  • Jennifer Soucie, M.Sc.

      Affiliations

    • Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Greg Garvin, M.D.

      Affiliations

    • Department of Radiology, St. Joseph’s Health Care, London, Ontario, Canada
    • ,
  • Leslie Vanderburgh, M.D.

      Affiliations

    • Department of Radiology, William Osler Health Center, Brampton, Ontario, Canada
    • ,
  • Stuart Bell, M.D.

      Affiliations

    • Department of Medical Imaging, Sunnybrook and Women’s College Health Sciences Center, Toronto, Ontario, Canada
    • ,
  • Ontario Uterine Fibroid Embolization Collaborative Group

Received 19 April 2002 ,Revised 16 September 2002 ,Accepted 16 September 2002.

References 

  1. Greenberg MD, Kazamel IG. Medical and socioeconomic impact of uterine fibroids. Obstet Gynecol Clin N Am. 1995;22:625–636
  2. Vollenhoven B. Introduction (the epidemiology of uterine leiomyomas). Baillieres Clin Obstet Gynaecol. 1998;12:169–176
  3. Millar WJ. Hysterectomy, 1981/82 to 1996/97. Health reports (Statistics Canada, Catalogue 82-003) 2001;12:9–22
  4. Lepine LA, Hillis SD, Marchbanks PA, Roonin LM, Morrow B, Kieke BA, et al.  Hysterectomy surveillance—United States, 1980–1993. MMW Morb Mort Wkly Rep CDC Surveill Summ. 1997;46:1–15
  5. Bachman GA. Hysterectomy, a critical review. J Reprod Med. 1990;35:839–862
  6. Carlson KJ, Miller BA, Fowler FJ. The Maine women’s health study. 1. Outcomes of hysterectomy. Obstet Gynecol. 1994;83:556–565
  7. Ravina JH, Herbreteau D, Ciraru-Vigneron N, Bouret JM, Houdart E, Aymard A, et al.  Arterial embolization to treat uterine myomata. Lancet. 1995;346:671–672
  8. Worthington-Kirsch RL, Popky GL, Hutchins FL. Uterine artery embolization for the management of leiomyomas (quality-of-life assessment and clinical response). Radiology. 1998;208:625–629
  9. Walker W, Green A, Sutton C. Bilateral uterine artery embolization for myoma (results, complications and failures). Min Invas Ther Allied Technol. 1998;8:449–454
  10. Goodwin SC, McLucas B, Lee M, Chen G, Perrella R, Vedantham S, et al.  Uterine artery embolization for the treatment of uterine leiomyomata; midterm results. J Vasc Interv Radiol. 1999;10:1159–1165
  11. Hutchins FL, Worthington-Kirsch R, Berkowitz RP. Selective uterine artery embolization as primary treatment for symptomatic leiomyomata uteri. J Am Assoc Gynecol Laparosc. 1999;6:279–284
  12. Spies JB, Scialli AR, Jha RC, Imaoka I, Ascher SM, Fraga VM, et al.  Initial results from uterine fibroid embolization for symptomatic leiomyomata. J Vasc Interv Radiol. 1999;10:1149–1157
  13. Siskin GP, Stainken BF, Dowling K, Meo P, Ahn J, Dolen EG. Outpatient uterine artery embolization for symptomatic uterine fibroids (experience in 49 patients). J Vasc Interv Radiol. 2000;11:305–311
  14. Pelage JP, LeDref O, Soyer P, Kardache M, Dahan H, Abitbol M, et al.  Fibroid-related menorrhagia (treatment with superselective embolization of the uterine arteries and mid-term follow-up). Radiology. 2000;215:428–431
  15. Brunereau L, Herbreteau D, Gallas S, Cottier JP, Lebrun JL, Tranhquart F, et al.  Uterine artery embolization in the primary treatment of uterine leiomyomas (technical features and prospective follow up with clinical and sonographic examinations in 58 patients). AJR. 2000;175:1267–1272
  16. Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, et al.  Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol. 1997;90:967–973
  17. Wilcox LS, Koonin LM, Pokras R, Strauss LT, Xia Z, Paterson R. Hysterectomy in the United States, 1988–1990. Obstet Gynecol. 1994;83:549–555
  18. Kjerulff KH, Guzinkis GM, Langenberg PW, Stolley PD, Adler NE, Kazandjian VA. Hysterectomy and race. Obstet Gynecol. 1993;82:757–764
  19. Palmer JR, Rao RS, Adams-Campbell LL, Rosenberg L. Correlates of hysterectomy among African-American women. Am J Epidemiol. 1999;150:1309–1315
  20. Gilmore J. Body mass index and health. Health reports (Statistics Canada, Catalogue 82-003) 1999;11:31–43
  21. Hagenfeldt K, Brorsson B, Bernstein SJ. Hysterectomy ratings of appropriateness. Swedish Council on Technology Assessment in Health Care, SBU Report No. 125E, Printcenter, Stockholm, Sweden 1995
  22. Orsini L, Salardi S, Pilu G, Bovicelli L, Cacciari E. Pelvic organs in premenarcheal girls (real-time ultrasonography). Radiology. 1984;153:113–116
  23. Normand J. Women in Canada, a statistical report (Statistics Canada, Catalogue 89-503E) 1995:54–63
  24. Kjerulff K, Lanenberg P, Guzinkis G. The socioeconomic correlates of hysterectomies in the United States. Am J Pub Health. 1993;83:106–108
  25. Harlow BL, Barbieri RL. Influence of education on risk of hysterectomy before age 45 years. Am J Epidemiol. 1999;150:843–847
  26. Faerstein E, Szklo M, Rosenshein N. Risk factors for uterine leiomyoma (a practice-based case-control study). Am J Epidemiol. 2001;153:1–10
  27. Swain L, Catlin G, Beaudet MP. The national population health survey—its longitudinal nature. Health reports (Statistics Canada, Catalogue 82-003) 1999;10:69–82
  28. Kjerulff KH, Langenberg P, Seidman JD, Stolley PD, Guzinski GM. Uterine leiomyomas. Racial differences in severity, symptoms and age at diagnosis. J Reprod Med. 1996;41:483–490
  29. Vilos G, Lefebvre G. Guidelines for the management of abnormal uterine bleeding. J Soc Obstet Gynaecol Can. 2001;23:704–709
  30. Spies JB, Warren EH, Mathias SD, Walsh SM, Roth AR, Pentecost MJ. Uterine fibroid embolization (measurement of health related quality of life before and after therapy). J Vasc Interv Radiol. 1999;10:1293–1303
  31. Rowe MK, Kanouse DE, Mittman BS, Bernstein SJ. Quality of life among women undergoing hysterectomies. Obstet Gynecol. 1999;93:915–921

☆ The Ontario Uterine Fibroid Embolization Trial was funded in part by the Boston Scientific Corporation.

PII: S0015-0282(02)04539-9

Fertility and Sterility
Volume 79, Issue 1 , Pages 112-119 , January 2003

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