Fertility and Sterility
Volume 82, Issue 1 , Pages 244-246 , July 2004

Insulin levels, insulin resistance, and leptin levels are not associated with the development of ovarian hyperstimulation syndrome

Received 25 April 2003 ,Revised 31 October 2003 ,Accepted 31 October 2003.

References 

  1. Golan A, Ron-El R, Herman A, Soffer Y, Waniraub Z, Caspi E. Ovarian hyperstimulation syndrome. An update review. Obstet Gynaecol Surv. 1989;44:430–440
  2. Navot D, Bergh PA, Laufer N. Ovarian hyperstimulation syndrome in novel reproductive technologies prevention and treatment. Fertil Steril. 1992;58:249–261
  3. Dunaif A. Insulin resistance and the polycystic ovary syndrome (mechanism and implications for pathogenesis). Endocrinol Rev. 1997;18:774–800
  4. Fulghesu AM, Villa P, Pavone V, Guido M, Apa R, Caruso A, et al.  The impact of insulin secretion on the ovarian response to exogenous gonadotrophins in polycystic ovary syndrome. J Clin Endocrinol Metab. 1997;82:644–648
  5. Elmquist JK. Anatomic basis of leptin action in the hypothalamus. Front Horm Res. 2000;26:21–41
  6. Moschos S, Chan L, Mantzoros A. Leptin and reproduction (a review). Fertil Steril. 2002;77:433–444
  7. Karlsson C, Lindell K, Svensson E. Expression of functional leptin receptors in the human ovary. J Clin Endocrinol Metab. 1997;82:4144–4148
  8. Lindheim SR, Sauer MV, Carmina E, Chang PL, Zimmerman R, Lobo RA. Circulating leptin levels during ovulation induction (relation to adiposity and ovarian morphology). Fertil Steril. 2000;73:493–498
  9. Legro RS, Finegood D, Dunaif A. A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 1998;83:2694–2698
  10. Fedorcsàk P, Dale PO, Storeng R, Tanbo T, Åbyholm T. The impact of obesity and insulin resistance on the outcome of IVF or ICSI in women with polycystic ovarian syndrome. Hum Reprod. 2001;16:1086–1091
  11. Mantzoros C, Cramer D, Liberman F, Barbieri R. Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome. Hum Reprod. 2000;15:539–544
  12. Antczak M, Van Blerkom J. Temporal and spatial aspects of fragmentation in early human embryos (possible effects on developmental competence and association with the differential elimination of regulatory proteins from polarized domains). Hum Reprod. 1999;14:429–447

PII: S0015-0282(04)00531-X

doi: 10.1016/j.fertnstert.2003.10.056

Fertility and Sterility
Volume 82, Issue 1 , Pages 244-246 , July 2004

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