Fertility and Sterility
Volume 82, Issue 1 , Pages 237-238, July 2004

Serum testosterone levels in patients with nonmosaic Klinefelter syndrome after testicular sperm extraction for intracytoplasmic sperm injection

  • Hiroshi Okada, M.D., Ph.D.

      Affiliations

    • Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • Department of Urology, Teikyo University School of Medicine, Tokyo, Japan
    • Corresponding Author InformationReprint requests: Hiroshi Okada, M.D., Ph.D., Department of Urology, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo 173-8605, Japan , Tel: +81 78 382 6155(FAX: +81-3-3964-8934).
    • ,
  • Toshiro Shirakawa, M.D., Ph.D.

      Affiliations

    • Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Tomomoto Ishikawa, M.D.

      Affiliations

    • Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Kazumasa Goda, M.D.

      Affiliations

    • Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Masato Fujisawa, M.D., Ph.D.

      Affiliations

    • Department of Urology, Kawasaki Medical University, Kurashiki, Japan
    • ,
  • Sadao Kamidono, M.D., Ph.D.

      Affiliations

    • Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan

Received 19 June 2003; received in revised form 25 November 2003; accepted 25 November 2003.

Abstract 

We measured testosterone levels in 24 patients with nonmosaic Klinefelter syndrome before and at 6 and 12 months after conventional or microdissection testicular sperm extraction. Testosterone levels decreased after surgery by either technique, and they did not recover to baseline concentrations, even when using less invasive microdissection techniques.

Keywords:  Testicular sperm extraction, microsurgery, testosterone, assisted reproductive technology, Klinefelter syndrome

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PII: S0015-0282(04)00548-5

doi:10.1016/j.fertnstert.2003.11.047

Fertility and Sterility
Volume 82, Issue 1 , Pages 237-238, July 2004

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