Low-molecular-weight dextran infusion is more effective for the treatment of hemoconcentration due to severe ovarian hyperstimulation syndrome than human albumin infusion

Endo, Toshiaki; Kitajima, Yoshimitsu; Hayashi, Takuhiro; Fujii, Miho; Hata, Hiroshi; Azumaguchi, Atsushi

doi:10.1016/j.fertnstert.2004.04.045

« Previous Next »Fertility and Sterility
Volume 82, Issue 5 , Pages 1449-1451, November 2004

Low-molecular-weight dextran infusion is more effective for the treatment of hemoconcentration due to severe ovarian hyperstimulation syndrome than human albumin infusion

Toshiaki Endo, M.D.
- Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan,
- Reprint requests: Toshiaki Endo, M.D., Sapporo Medical University School of Medicine, Department of Obstetrics and Gynecology, South 1 West 16 Chuou-ku, Sapporo 060-8543, Japan (FAX: 81-11-614-0860
Yoshimitsu Kitajima, M.D.
- Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan,
Takuhiro Hayashi, M.D.
- Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan,
Miho Fujii, M.D.
- Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan,
Hiroshi Hata, M.D.
- Department of Obstetrics and Gynecology, Sapporo Toho Hospital, Sapporo, Japan,
Atsushi Azumaguchi, M.D.
- Department of Obstetrics and Gynecology, Tonan Hospital, Sapporo, Japan

Received 3 December 2003; received in revised form 9 April 2004; accepted 9 April 2004.

The most severe complication of ovarian hyperstimulation syndrome (OHSS) is thromboembolism, which is related to hemoconcentration. Dextran 40 infusion has greater effectiveness for the treatment of hemoconcentration due to OHSS than does human albumin infusion.