Fertility and Sterility
Volume 82, Issue 6 , Pages 1714-1715 , December 2004

Whole sheep ovary cryopreservation and transplantation

Recipient of the American Society of Reproductive Medicine SRS prize (Oct. 2001) and a prize from the Israeli Fertility Society (April 2002).

  • Ariel Revel, M.D.

      Affiliations

    • Hadassah University Hospital, Jerusalem
    • ,
  • Amir Elami, M.D.

      Affiliations

    • Hadassah University Hospital, Jerusalem
    • ,
  • Amir Bor, D.V.M.

      Affiliations

    • Institute of Animal Science, Agricultural Research Organization (ARO), the Volcani Center, Bet Dagan, Israel
    • ,
  • Saar Yavin, M.Sc.

      Affiliations

    • Institute of Animal Science, Agricultural Research Organization (ARO), the Volcani Center, Bet Dagan, Israel
    • ,
  • Yehudit Natan, M.Sc.

      Affiliations

    • Institute of Animal Science, Agricultural Research Organization (ARO), the Volcani Center, Bet Dagan, Israel
    • ,
  • Amir Arav, D.V.M., Ph.D.

      Affiliations

    • Institute of Animal Science, Agricultural Research Organization (ARO), the Volcani Center, Bet Dagan, Israel
    • Corresponding Author InformationReprint requests: Amir Arav, D.V.M., Ph.D., Institute of Animal Science, Agricultural Research Organization (ARO), P.O. Box 6, Bet Dagan 50250, Israel (FAX: 972-8-9475075

Received 12 August 2002 ,Revised 29 June 2004 ,Accepted 29 June 2004.

References 

  1. Boring CC , Squires TS , Tong T . Cancer statistics . CA Cancer J Clin . 1991;41:19–36
  2. Chen C . Pregnancy after human oocyte cryopreservation . Lancet . 1986;1:884–886
  3. Porcu E , Fabbri R , Damiano G , Giunchi S , Fratto R , Ciotti PM , et al.  Clinical experience and applications of oocytes cryopreservation . Mol Cell Endocrinol . 2000;169:33–37
  4. Fabbri R , Porcu E , Marsella T , Rocchetta G , Venturoli S , Flamigni C . Human oocyte cryopreservation: new perspectives regarding oocyte survival . Hum Reprod . 2001;16:411–416
  5. Gosden RG , Baird DT , Wade JC , Webb R . Restoration of fertility to oophorectomized sheep by ovarian autografts stored at −196 degrees C . Hum Reprod . 1994;9:597–603
  6. Baird DT , Webb R , Campbell BK , Harkness LM , Gosden RG . Long-term ovarian function in sheep after ovariectomy and transplantation of autografts stored at −196 C . Endocrinology . 1999;140:462–471
  7. Smitz J , Cortvrindt R . Oocyte in-vitro maturation and follicle culture: current clinical achievements and future directions . Hum Reprod . 1999;14(Suppl 1):145–161
  8. Abir R , Franks S , Mobberley MA , Moore PA , Margara RA , Winston RM . Mechanical isolation and in vitro growth of preantral and small antral human follicles . Fertil Steril . 1997;68:682–688
  9. Weissman A , Gotlieb L , Colgan T , Jurisicova A , Greenblatt EM , Casper RF . Preliminary experience with subcutaneous human ovarian cortex transplantation in the NOD-SCID mouse . Biol Reprod . 1999;60:1462–1467
  10. Revel A , Raanani H , Wang P , Chian RC , Casper RF . Oocyte retrieval and in vitro maturation from frozen thawed human ovarian cortex transplanted in immune suppressed mice . [abstract] Hum Reprod . 2001;15:13
  11. Nisolle M , Casanas-Roux F , Qu J , Motta P , Donnez J . Histologic and ultra structural evaluation of fresh and frozen-thawed human ovarian xenografts in nude mice . Fertil Steril . 2000;74:122–129
  12. Zook N , Hussmann J , Brown R , Russell R , Kucan J , Roth A , et al.  Microcirculatory studies of frostbite injury . Ann Plast Surg . 1998;40:246–255
  13. Shaw JM , Trounson AO . Experimental models for ovarian tissue and immature follicles . Semin Reprod Med . 2002;20:51–62
  14. Wang X , Chen H , Yin H , Kim SS , Lin Tan S , Gosden RG . Fertility after intact ovary transplantation . Nature . 2002;415:385

 Supported by a grant from the Israeli Academy of Sciences and a grant from IMT Ltd.

PII: S0015-0282(04)02434-3

doi: 10.1016/j.fertnstert.2004.06.046

Fertility and Sterility
Volume 82, Issue 6 , Pages 1714-1715 , December 2004

Article Tools

* Image Usage & Resolution