Fertility and Sterility
Volume 83, Issue 4 , Pages 1041.e1-1041.e3 , April 2005

Live birth of healthy triplets after in vitro fertilization and embryo transfer in an acromegalic woman with elevated growth hormone

  • Navid Esfandiari, D.V.M., Ph.D.
    • ,
  • Lynda Gotlieb, R.N.
    • ,
  • Robert F. Casper, M.D., F.R.C.S.(C.)

      Affiliations

    • Corresponding Author InformationReprint requests: Robert F. Casper, M.D., F.R.C.S.(C.), Toronto Centre for Advanced Reproductive Technology, 210-150 Bloor Street West, Toronto, Ontario, M5S 2X9, Canada (FAX: 416-972-0036)

Received 22 June 2004 ,Revised 5 October 2004 ,Accepted 5 October 2004.

References 

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  2. Molitch ME . Clinical manifestations of acromegaly . Endocrinol Metab Clin North Am . 1992;21:597–614
  3. Advis JP , White SS , Ojeda SR . Activation of growth hormone short loop negative feedback delays puberty in the female rat . Endocrinology . 1981;108:1343–1352
  4. Hsu CJ , Hammond JM . Concomitant effects of growth hormone on secretion of insulin-like growth factor I and progesterone by cultured porcine granulosa cells . Endocrinology . 1987;121:1343–1348
  5. Lucy MC , Bilby CR , Kirby CJ , Yuan W , Boyd CK . Role of growth hormone in development and maintenance of follicles and corpora lutea . J Reprod Fertil Suppl . 1999;54:49–59
  6. Mondschein JS , Canning SF , Miller DQ , Hammond JM . Insulin-like growth factors (IGFs) as autocrine/paracrine regulators of granulose cell differentiation and growth . Biol Reprod . 1989;40:79–85
  7. Herman-Bonert V , Seliverstov M , Melmed S . Pregnancy outcome in acromegaly: successful therapeutic outcome . J Clin Endocrinol Metab . 1998;83:727–731
  8. Danilovich NA , Bartke A , Winters TA . Ovarian follicle apoptosis in bovine growth hormone transgenic mice . Biol Reprod . 2000;62:103–107
  9. Ovesen P . Synergistic effects of growth hormone and insulin-like growth factor-I on differentiation and replication of cultured human luteinized granulose cells . Acta Obstet Gynecol Scand . 1998;77:487–491
  10. Bevers MM , Izadyar F . Role of growth hormone and growth hormone receptor in oocyte maturation . Mol Cell Endocrinol . 2002;197:173–178
  11. Cecim M , Kerr J , Bartke A . Effects of bovine growth hormone (bGH) transgene expression or bGH treatment on reproductive functions in female mice . Biol Reprod . 1995;52:1144–1148
  12. Brun JM , Bloch B , Bugnon C , Putelat R . Twin pregnancy following bromocriptine in an acromegalic patient staying sterile after removal of a pituitary adenoma . Immunocytochemical study of the tumor. Ann Endocrinol (Paris) . 1979;40:551–552

PII: S0015-0282(04)03171-1

doi: 10.1016/j.fertnstert.2004.10.034

Fertility and Sterility
Volume 83, Issue 4 , Pages 1041.e1-1041.e3 , April 2005

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