Fertility and Sterility
Volume 84, Issue 5 , Pages 1320-1324, November 2005

Risk of birth defects among children conceived with assisted reproductive technology: providing an epidemiologic context to the data

  • Laura A. Schieve, Ph.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Laura A. Schieve, Ph.D., Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Mail Stop E-86, 1600 Clifton Road, Atlanta, Georgia 30333 (FAX: 404-498-3550).
  • ,
  • Sonja A. Rasmussen, M.D.
  • ,
  • Jennita Reefhuis, Ph.D.

Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia

Received 22 April 2005; received in revised form 22 April 2005; accepted 22 April 2005.

Studies of assisted reproductive technology (ART) and birth defects must be scrutinized and appropriately interpreted in the context of their limitations. The recent findings reported by Klemetti et al. are compelling, given the study’s many strengths, and add to the accumulating evidence suggestive of an association between ART and birth defects.

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PII: S0015-0282(05)02925-0

doi:10.1016/j.fertnstert.2005.04.066

Fertility and Sterility
Volume 84, Issue 5 , Pages 1320-1324, November 2005