Fertility and Sterility
Volume 84, Issue 5 , Pages 1320-1324 , November 2005

Risk of birth defects among children conceived with assisted reproductive technology: providing an epidemiologic context to the data

  • Laura A. Schieve, Ph.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Laura A. Schieve, Ph.D., Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Mail Stop E-86, 1600 Clifton Road, Atlanta, Georgia 30333 (FAX: 404-498-3550).
    • ,
  • Sonja A. Rasmussen, M.D.
    • ,
  • Jennita Reefhuis, Ph.D.

Received 22 April 2005 ,Revised 22 April 2005 ,Accepted 22 April 2005.

References 

  1. Centers for Disease Control and Prevention, American Society for Reproductive Medicine, Society for Assisted Reproductive Technology . 2002 assisted reproductive technology success rates (national summary and fertility clinic reports) . Atlanta, GA: Centers for Disease Control and Prevention; 2004;
  2. Wright VC , Schieve LA , Reynolds MA , Jeng G . Assisted reproductive technology surveillance—United States, 2002 . MMWR Surveill Summ . 2005;54:1–24
  3. Jackson RA , Gibson KA , Wu YW , Croughan MS . Perinatal outcomes in singletons following in vitro fertilization (a meta-analysis) . Obstet Gynecol . 2004;103:551–563
  4. Helmerhorst FM , Perquin DAM Donker D , Keirse MJNC . Perinatal outcome of singletons and twins after assisted conception (a systematic review of controlled studies) . BMJ . 2004;328:261–265
  5. Schieve LA , Ferre C , Peterson HB , Macaluso M , Reynolds MA , Wright VC . Perinatal outcome among singleton infants conceived through assisted reproductive technology in the United States . Obstet Gynecol . 2004;103:1144–1153
  6. Hansen M , Kurinczuk JJ , Bower C , Webb S . The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization . N Engl J Med . 2002;346:725–730
  7. Ericson A , Kallen B . Congenital malformations in infants born after IVF (a population-based study) . Hum Reprod . 2001;16:504–509
  8. Wennerholm UB , Bergh C , Hamberger L , Lundin K , Nilsson L , Wikland M , et al.   Incidence of congenital malformations in children born after ICSI . Hum Reprod . 2000;15:944–948
  9. Koivurova S , Hartikainen AL , Gissler M , Hemminki E , Sovio U , Jarvelin MR . Neonatal outcome and congenital malformations in children born after in-vitro fertilization . Hum Reprod . 2002;17:1391–1398
  10. Sutcliff AG , Taylor B , Saunders K , Thornton S , Lieberman BA , Grudzinskas JG . Outcome in the second year of life after in-vitro fertilization by intracytoplasmic sperm injection (a UK case-control study) . Lancet . 2001;357:2080–2084
  11. Westergaard HB , Johansen AMT , Erb K , Andersen AN . Danish national in-vitro fertilization registry 1994 and 1995 (a controlled study of births, malformations and cytogenetic findings) . Hum Reprod . 1999;14:1896–1902
  12. Klemetti R , Gissler M , Sévon T , Koivurova S , Ritvanen A , Hemminki E . Children born after assisted fertilization have an increased rate of major congenital anomalies . Fertil Steril . 2005;84:1300–1307
  13. Khoury MJ , James LM , Flanders D , Erickson JD . Interpretation of recurring weak associations obtained from epidemiologic studies of suspected human teratogens . Teratology . 1992;46:69–77
  14. Rasmussen SA , Mulinare J , Khoury MJ , Maloney EK . Evaluation of birth defect histories obtained through maternal interviews . Am J Hum Genet . 1990;46:478–485
  15. Reefhuis J , Honein MA . Maternal age and non-chromosomal birth defects, Atlanta—1968–2000 (teenager or thirty-something, who is at risk?) . Birth Defects Res A Clin Mol Teratol . 2004;70:572–579

PII: S0015-0282(05)02925-0

doi: 10.1016/j.fertnstert.2005.04.066

Fertility and Sterility
Volume 84, Issue 5 , Pages 1320-1324 , November 2005

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