Fertility and Sterility
Volume 84, Issue 5 , Pages 1325-1326 , November 2005

Do children born after assisted reproductive technology have a higher incidence of birth defects?

  • Francois Olivennes, M.D., Ph.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Francois Olivennes, M.D., Ph.D., Medecine de la Reproduction, Service de Gynecologie Obstetrique II, 123 Bd Port Royal, Paris 75014, France (FAX: 33-1-58-41-18-70).

Received 11 May 2005 ,Revised 11 May 2005 ,Accepted 11 May 2005.

References 

  1. Klemetti R , Gissler M , Sévon T , Koivurova S , Ritvanen A , Hemminki E . Children born after assisted fertilization have an increased rate of major congenital anomalies . Fertil Steril . 2005;84:1300–1307
  2. Kurinczuk J , Bower C . Birth defects in infants conceived by intracytoplasmic sperm injection (an alternative interpretation) . BMJ . 1997;315:1260–1265
  3. Bonduelle M , Legein J , Buysse A , Van Assche E , Wisanto A , Devroey P , et al.   Prospective follow-up study of 423 children born after intracytoplasmic sperm injection . Hum Reprod . 1996;11:1558–1564
  4. Hansen M , Bower C , Milne E , de Klerk N , Kurinczuk JJ . Assisted reproductive technologies and the risk of birth defects—a systematic review . Hum Reprod . 2005;20:328–338
  5. Ghazi HA , Spielberger C , Kallen B . Delivery outcome after infertility—a registry study . Fertil Steril . 1991;55:726–732

PII: S0015-0282(05)02931-6

doi: 10.1016/j.fertnstert.2005.05.044

Fertility and Sterility
Volume 84, Issue 5 , Pages 1325-1326 , November 2005