Fertility and Sterility
Volume 85, Issue 3 , Pages 640-645 , March 2006

Sperm cryopreservation in oncological patients: a 14-year follow-up study

  • Marcos Meseguer, Ph.D.

      Affiliations

    • Instituto Universitario Valenciano de Infertilidad, Universidad de Valencia, Valencia, Spain
    • Fundación Instituto Valenciano de Infertilidad, Valencia, Spain
    • Corresponding Author InformationReprint requests: Marcos Meseguer, Ph.D., Instituto Valenciano de Infertilidad, Plaza de la Policía Local, 3, Valencia 46015, Spain (FAX: 34 96 3050999)
  • ,
  • Nancy Molina, M.D.

      Affiliations

    • Instituto Universitario Valenciano de Infertilidad, Universidad de Valencia, Valencia, Spain
  • ,
  • Juan A. García-Velasco, M.D.

      Affiliations

    • Instituto Valenciano de Infertilidad Madrid, Madrid, Spain
  • ,
  • Jose Remohí

      Affiliations

    • Instituto Universitario Valenciano de Infertilidad, Universidad de Valencia, Valencia, Spain
  • ,
  • Antonio Pellicer

      Affiliations

    • Instituto Universitario Valenciano de Infertilidad, Universidad de Valencia, Valencia, Spain
    • Hospital Universitario Dr. Peset, Valencia, Spain
  • ,
  • Nicolás Garrido, Ph.D.

      Affiliations

    • Instituto Universitario Valenciano de Infertilidad, Universidad de Valencia, Valencia, Spain
    • Fundación Instituto Valenciano de Infertilidad, Valencia, Spain

Received 19 January 2005 ,Revised 8 August 2005 ,Accepted 8 August 2005.

References 

  1. American Cancer Society . In: Cancer facts and figures 2002, American Cancer Society statistics . 2002;p. 5–18 Available at: http://www.cancer.org/docroot/STT/content/STT_1X_cancerFacts_Figures_2004.asp.
  2. Meistrich ML . Effects of chemotherapy and radiotherapy on spermatogenesis . Eur Urol . 1993;23:136–142
  3. Stuart NSA , Woodroffe CM , Grundy R , Cullen MH . Long term toxicity of chemotherapy for testicular cancer—the cost of cure . Br J Oncol . 1992;61:479–484
  4. Naysmith TE , Blake DA , Harvey VJ , Johnson NP . Do men undergoing sterilizing cancer treatments have a fertile future? . Hum Reprod . 1998;13:3250–3255
  5. Schrader M , Muller M , Straub B , Miller K . The impact of chemotherapy on male fertility (a survey of the biologic basis and clinical aspects) . Reprod Toxicol . 2001;15:611–617
  6. Lass A, Akagbosu F, Abusheikha N, Hassouneh M, Blayney M, Avery S, et al. A programme of semen cryopreservation for patients with malignant disease in a tertiary infertility centre (lessons from 8 years’ experience) . Hum Reprod . 1998;13:3256–3261
  7. Bahadur G , Ling KL , Hart R , Ralph D , Wafa R , Ashraf A , et al.   Semen quality and cryopreservation in adolescent cancer patients . Hum Reprod . 2002;17:3157–3161
  8. Arnoldi M , Somigliana E , Paffoni A , Restelli L , Brambilla ME , Ragni G . Reproductive prognosis in male cancer patients with azoospermia at the time of the diagnosis of malignancy . Hum Reprod . 2004;(Suppl 1):i24
  9. Zapzalka DM , Redmon JB , Pryor JL , Ragni A . Survey of oncologists regarding sperm cryopreservation and assisted reproductive techniques for male cancer patients . Cancer . 1999;86:1812–1817
  10. Allen C , Keane D , Harrison RF . A survey of Irish consultants regarding awareness of sperm freezing and assisted reproduction . Med J . 2003;96:23–25
  11. Bazeos A , Al Sdhawaf T , Lower A , Wilson C , Grudzinskas J . Preservation of reproductive capacity in cancer patients . Reprod Technol . 1999;10:42–49
  12. Kliesch S , Kamischke A , Nieschlag E . Cryopreservation of human sperm . In:  Nieschlag E ,  Behre H editor. Andrology. Male reproductive health and dysfunction . Berlin: Springer Verlag; 1997;p. 347–355
  13. Rousillon E , Pariene JL , Hostyn B , Merian G , Ferriere JM , Le Guillou M . Fertilité masculine après chimiothérapie (a propos d’une série de 26 patients traites pur cancer du testicule stade 1) . Andrologie . 1999;9:42–47
  14. Meseguer M, Garrido N, Remohí J, Pellicer A, Simon C, Martinez-Jabaloyas JM, et al. Testicular sperm extraction (TESE) and ICSI in patients with permanent azoospermia after chemotherapy . Hum Reprod . 2003;18:1281–1285
  15. Meseguer M , Garrido N , Simon C , Pellicer A , Remohi J . Concentration of glutathione and expression of glutathione peroxidases 1 and 4 in fresh sperm provide a forecast of the outcome of cryopreservation of human spermatozoa . J Androl . 2004;25:773–780
  16. Meseguer M , Garrido N , Martinez-Conejero JA , Simon C , Pellicer A , Remohi J . Role of cholesterol, calcium, and mitochondrial activity in the susceptibility for cryodamage after a cycle of freezing and thawing . Fertil Steril . 2004;81:588–594
  17. Gil-Salom M, Romero J, Minguéz Y, Rubio C, De los Santos MJ, Remohi P, et al. Pregnancies after intracytoplasmic sperm injection with cryopreserved testicular spermatozoa . Hum Reprod . 1996;11:1309–1313
  18. Díaz I , Navarro J , Blasco L , Simón C , Pellicer A , Remohí J . Impact of stage II-IV endometriosis on recipients of sibling oocytes (matched case control study) . Fertil Steril . 2000;74:31–34
  19. Garrido N , Meseguer M , Bellver J , Remohi J , Simon C , Pellicer A . Report of the results of a 2 year programme of sperm wash and ICSI treatment for human immunodeficiency virus and hepatitis C virus serodiscordant couples . Hum Reprod . 2004;19:2581–2586
  20. Meseguer M , Garrido N , Remohi J , Pellicer A , Gil-Salom M . Testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) in hypogonadotropic hypogonadism with persistent azoospermia after hormonal therapy . J Assist Reprod Genet . 2004;21:91–94
  21. Milligan DW , Hughes R , Lindsay KS . Semen cryopreservation in men undergoing cancer chemotherapy—a UK survey . Br J Cancer . 1989;60:966–967
  22. Chung K , Irani J , Knee G , Efymow B , Blasco L , Patrizio P . Sperm cryopreservation for male patients with cancer (an epidemiological analysis at the University of Pennsylvania) . Eur J Obstet Gynecol Reprod Biol . 2004;113(Suppl 1):S7–S11
  23. Centro Nacional de Epidemiología. Informe sobre la salud de los Españoles. Cancer. Available at: http://193.146.50.130/htdocs/cancer//salud-cancer-2003.pdf.
  24. Martin RH , Ernst S , Rademaker A , Barclay L , Ko E , Summers N . Analysis of sperm chromosome complements before, during, and after chemotherapy . Cancer Genet Cytogenet . 1999;108:133–136
  25. Arnon J , Meirow D , Lewis-Roness H , Ornoy A . Genetic and teratogenic effects of cancer treatments on gametes and embryos . Hum Reprod Upd . 2001;7:394–403
  26. Hallak J , Sharma RK , Thomas AJ , Agarwal A . Why cancer patients request disposal of cryopreserved semen specimens posttherapy (a retrospective study) . Fertil Steril . 1998;69:889–893
  27. Tournaye H , Camus M , Bollen N , Wisanto A , Van Steirteghem AC , Devroey P . In vitro fertilization techniques with frozen-thawed sperm (a method for preserving the progenitive potential of Hodgkin patients) . Fertil Steril . 1991;55:443–445
  28. Sanger WG , Olson JH , Sherman JK . Semen cryobanking for men with cancer—criteria change . Fertil Steril . 1992;58:1024–1027
  29. Kelleher S, Wishart SM, Liu PY, Turner L, Di Pierro I, Conway AJ, et al. Long-term outcomes of elective human sperm cryostorage . Hum Reprod . 2001;16:2632–2639

PII: S0015-0282(05)03936-1

doi: 10.1016/j.fertnstert.2005.08.022

Fertility and Sterility
Volume 85, Issue 3 , Pages 640-645 , March 2006