Fertility and Sterility
Volume 86, Issue 1 , Pages 64-69 , July 2006

Embryo quality is more important for younger women whereas age is more important for older women with regard to in vitro fertilization outcome and multiple pregnancy

  • Tsung-Hsien Lee, M.D., M.Sc.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan
    • Department of Obstetrics and Gynecology, Taipei County Hospital, Sanchong, Taiwan
    • ,
  • Chin-Der Chen, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Yi-Yi Tsai, M.Sc.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Li-Jung Chang, M.Sc.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Hong-Nerng Ho, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • ,
  • Yu-Shih Yang, M.D., Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationReprint requests: Yu-Shih Yang, M.D., Ph.D., Department of Obstetrics and Gynecology, National Taiwan University Hospital, No. 7, Chung-Shan South Road, 100, Taipei, Taiwan (FAX: 886-2-23418557).

Received 30 June 2005 ,Accepted 30 November 2005.

References 

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  9. Roseboom TJ , Vermeiden JP , Schoute E , Lens JW , Schats R . The probability of pregnancy after embryo transfer is affected by the age of the patient, cause of infertility, number of embryos transferred and the average morphology score, as revealed by multiple logistic regression analysis . Hum Reprod . 1995;10:3035–3041
  10. Hu Y , Maxson WS , Hoffman DI , Ory SJ , Eager S , Dupre J , et al.   Maximizing pregnancy rates and limiting higher-order multiple conceptions by determining the optimal number of embryos to transfer based on quality . Fertil Steril . 1998;69:650–657
  11. Steer CV , Mills CL , Tan SL , Campbell S , Edwards RG . The cumulative embryo score (a predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme) . Hum Reprod . 1992;7:117–119
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  17. Thurin A , Hausken J , Hillensjo T , Jablonowska B , Pinborg A , Strandell A , et al.   Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization . N Engl J Med . 2004;351:2392–2402
  18. Strandell A , Bergh C , Lundin K . Selection of patients suitable for one-embryo transfer may reduce the rate of multiple births by half without impairment of overall birth rates . Hum Reprod . 2000;15:2520–2525
  19. ESHRE Campus Course Report . Prevention of twin pregnancies after IVF/ICSI by single embryo transfer . Hum Reprod . 2001;16:790–800
  20. Garenne M . Do women forget their births? A study of maternity histories in a rural area of Senegal (Niakhar) . Popul Bull UN . 1994;43–54
  21. van Kooij RJ , Looman CW , Habbema JD , Dorland M , te Velde ER . Age-dependent decrease in embryo implantation rate after in vitro fertilization . Fertil Steril . 1996;66:769–775
  22. Bar-Hava I , Ferber A , Ashkenazi J , Orvieto R , Kaplan B , Bar J , et al.   Does female age affect embryo morphology? . Gynecol Endocrinol . 1999;13:371–374
  23. Marquez C , Sandalinas M , Bahce M , Alikani M , Munne S . Chromosome abnormalities in 1255 cleavage-stage human embryos . Reprod Biomed Online . 2000;1:17–26
  24. Gianaroli L , Magli MC , Ferraretti AP , Fiorentino A , Garrisi J , Munne S . Preimplantation genetic diagnosis increases the implantation rate in human in vitro fertilization by avoiding the transfer of chromosomally abnormal embryos . Fertil Steril . 1997;68:1128–1131

PII: S0015-0282(06)00547-4

doi: 10.1016/j.fertnstert.2005.11.074

Fertility and Sterility
Volume 86, Issue 1 , Pages 64-69 , July 2006

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