Fertility and Sterility
Volume 86, Issue 1 , Pages 200-202, July 2006

Rescue intracytoplasmic sperm injection and preimplantation genetic diagnosis in combination can result in pregnancy

  • Catherine M. DeUgarte, M.D.

      Affiliations

    • Henry Ford Hospital, Detroit, Michigan
    • Corresponding Author InformationReprint requests: Catherine M. DeUgarte, M.D., 1500 Big Beaver Road, Troy, Michigan 48084 (FAX: 734-622-9668).
    • ,
  • Man Li, M.D., Ph.D.

      Affiliations

    • ART Reproductive Center, Beverly Hills, California
    • ,
  • Brigid Jordan, B.S.

      Affiliations

    • ART Reproductive Center, Beverly Hills, California
    • ,
  • David Hill, Ph.D.

      Affiliations

    • ART Reproductive Center, Beverly Hills, California
    • UCLA Medical Center, Los Angeles, California
    • ,
  • Alan DeCherney, M.D.

      Affiliations

    • UCLA Medical Center, Los Angeles, California
    • ,
  • Mark Surrey, M.D.

      Affiliations

    • ART Reproductive Center, Beverly Hills, California
    • UCLA Medical Center, Los Angeles, California

Received 9 August 2005; received in revised form 13 March 2006; accepted 13 March 2006.

Objective

To report the birth of a baby from the transfer of one embryo after rescue intracytoplasmic sperm injection (ICSI) and preimplantation genetic diagnosis (PGD).

Design

Case report.

Setting

IVF center.

Patient(s)

A 42-year-old G2P0020 woman with unexplained infertility.

Intervention(s)

Rescue ICSI followed by PGD.

Main Outcome Measure(s)

Pregnancy.

Result(s)

Rescue ICSI was performed on seven unfertilized oocytes, which resulted in three embryos. The PGD analysis revealed one normal embryo, which was transferred and resulted in pregnancy and delivery.

Conclusion(s)

Rescue ICSI in combination with PGD can result in a successful pregnancy.

Key Words:  Rescue ICSI , PGD , pregnancy

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PII: S0015-0282(06)01015-6

doi:10.1016/j.fertnstert.2006.03.021

Fertility and Sterility
Volume 86, Issue 1 , Pages 200-202, July 2006

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