Fertility and Sterility
Volume 87, Issue 6 , Pages 1444-1449 , June 2007

Lysed cell removal promotes frozen–thawed embryo development

Received 19 December 2005 ,Revised 7 November 2006 ,Accepted 7 November 2006.

References 

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  4. Van der Elst J, Van den Abbeel E, Vitrier S, Camus M, Devroey P, Van Steirteghem AC. Selective transfer of cryopreserved human embryos with further cleavage after thawing increases delivery and implantation rates. Hum Reprod. 1997;12:1513–1521
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  8. Jericho H, Wilton L, Gook DA, Edgar DH. A modified cryopreservation method increases the survival of human biopsied cleavage stage embryos. Hum Reprod. 2003;18:568–571
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  10. Van den Abbeel E, Camus M, Van Waesberghe L, Devroey P, van Steirteghem A. Viability of partially damaged human embryos after cryopreservation. Hum Reprod. 1997;12:2006–2010
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  12. Nagy ZP, Taylor T, Elliott T, Massey JB, Kort HI, Shapiro DB. Removal of lysed blastomeres from frozen–thawed embryos improves implantation and pregnancy rates in frozen embryo transfer cycles. Fertil Steril. 2005;84:1606–1612
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  14. Rienzi L, Ubaldi F, Iacobelli M, Minasi MG, Romano S, Ferrero S, et al. Development potential of fully intact and partly damaged cryopreserved embryos after laser-assisted removal of necrotic blastomeres and post-thaw culture selection. Fertil Steril. 2005;84:888–894
  15. Liu WX, Zheng Y, Luo MJ, Huang P, Yue LM, Wang L, et al. Effects of removal of necrotic blastomeres from mouse cryopreserved embryos on blastocyst formation and hatching. Theriogenology. 2005;15:64;1114–20

PII: S0015-0282(06)04490-6

doi: 10.1016/j.fertnstert.2006.11.064

Fertility and Sterility
Volume 87, Issue 6 , Pages 1444-1449 , June 2007