Fertility and Sterility
Volume 87, Issue 6 , Pages 1322-1326, June 2007

Bed rest after embryo transfer: a randomized controlled trial

  • Karen J. Purcell, M.D., Ph.D.

      Affiliations

    • Fertility Physicians of Northern California, San Jose, California
    • Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California
    • Corresponding Author InformationReprint requests: Karen Purcell, M.D., Ph.D., Fertility Physicians of Northern California, 2581 Samaritan Dr., Suite 302, San Jose, CA 95124 (FAX: 408-907-0950).
    • ,
  • Michael Schembri, M.S.

      Affiliations

    • Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California
    • ,
  • Tracey L. Telles, M.D.

      Affiliations

    • Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California
    • ,
  • Victor Y. Fujimoto, M.D.

      Affiliations

    • Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California
    • ,
  • Marcelle I. Cedars, M.D.

      Affiliations

    • Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California

Received 18 May 2006; received in revised form 3 October 2006; accepted 15 November 2006. published online 15 March 2007.

Objective

To determine whether bed rest after embryo transfer leads to improved pregnancy rates (PR).

Design

Randomized controlled trial.

Setting

University reproductive health clinic.

Patient(s)

Women undergoing IVF.

Intervention(s)

Patients undergoing 164 cycles of IVF were randomized to 30 minutes of bed rest after embryo transfer or immediate discharge from the clinic.

Main Outcome Measure(s)

Clinical PR defined by visualized fetal heart beat and ongoing PR defined by viable intrauterine gestation beyond 11 weeks.

Result(s)

The clinical and ongoing PR for both groups were 50% and 46.3%, respectively, with no statistically significant difference between the two groups.

Conclusion(s)

Thirty minutes of bed rest after embryo transfer does not improve PR.

Key Words: IVF, bed rest, embryo transfer, pregnancy rates, immediate ambulation

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 Supported by Obstetrics, Gynecology, and Reproductive Sciences, UCSF, San Francisco, CA 94115.

PII: S0015-0282(06)04531-6

doi:10.1016/j.fertnstert.2006.11.060

Fertility and Sterility
Volume 87, Issue 6 , Pages 1322-1326, June 2007

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