Fertility and Sterility
Volume 88, Issue 1 , Pages 244-246, July 2007

Prospective evaluation of the optimal time for selecting a single embryo for transfer: day 3 versus day 5

  • Nicolas H. Zech, M.D.

      Affiliations

    • Institute for Reproductive Medicine and Endocrinology, Bregenz, Austria
    • Corresponding Author InformationReprint requests: Nicolas H. Zech, M.D., Institute for Reproductive Medicine and Endocrinology, Roemerstrasse 2, A-6900 Bregenz, Austria (FAX: 43-5574-44836-9).
  • ,
  • Bernard Lejeune, M.D., PhD.

      Affiliations

    • Centre de Procréation Assistée du Centre Hospitalier Interrégional Edith Cavell (CHIREC), Braine l’Alleud, Brussels, Belgium
  • ,
  • Francoise Puissant, M.D.

      Affiliations

    • Centre de Procréation Assistée du Centre Hospitalier Interrégional Edith Cavell (CHIREC), Braine l’Alleud, Brussels, Belgium
  • ,
  • Sabine Vanderzwalmen, B.S.

      Affiliations

    • Centre de Procréation Assistée du Centre Hospitalier Interrégional Edith Cavell (CHIREC), Braine l’Alleud, Brussels, Belgium
  • ,
  • Herbert Zech, M.D., PhD.

      Affiliations

    • Institute for Reproductive Medicine and Endocrinology, Bregenz, Austria
  • ,
  • Pierre Vanderzwalmen, M.S.

      Affiliations

    • Institute for Reproductive Medicine and Endocrinology, Bregenz, Austria
    • Centre de Procréation Assistée du Centre Hospitalier Interrégional Edith Cavell (CHIREC), Braine l’Alleud, Brussels, Belgium

Received 10 July 2006; received in revised form 30 October 2006; accepted 16 November 2006. published online 08 February 2007.

To determine the best day for the selection and transfer of a single embryo, a prospective, randomized study was undertaken that compared the ongoing pregnancy rate (PR) after single embryo transfer (SET) on day 3 with that after single blastocyst transfer (SBT) on day 5. Our results show an overall significantly higher PR after SBT (32.8%) compared with SET (23.2%), and a PR of 40.8% after SBT versus 25.6% after excellent-quality embryos became available.

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PII: S0015-0282(06)04571-7

doi:10.1016/j.fertnstert.2006.11.070

Fertility and Sterility
Volume 88, Issue 1 , Pages 244-246, July 2007