Comparison of human chorionic gonadotropin and gonadotropin-releasing hormone agonist for final oocyte maturation in oocyte donor cycles

Shapiro, Bruce S.; Daneshmand, Said T.; Garner, Forest C.; Aguirre, Martha; Ross, Richard

doi:10.1016/j.fertnstert.2006.11.069

« Previous Next »Fertility and Sterility
Volume 88, Issue 1 , Pages 237-239, July 2007

Comparison of human chorionic gonadotropin and gonadotropin-releasing hormone agonist for final oocyte maturation in oocyte donor cycles

Bruce S. Shapiro, M.D.
- Fertility Center of Las Vegas, Las Vegas, Nevada
- Department of Obstetrics and Gynecology, University of Nevada School of Medicine, Las Vegas, Nevada
- Reprint requests: Bruce Shapiro, M.D., Fertility Center of Las Vegas, 8851 West Sahara Avenue, #100, Las Vegas, Nevada 89117 (FAX: 702-254-1213).
Said T. Daneshmand, M.D.
- Fertility Center of Las Vegas, Las Vegas, Nevada
- Department of Obstetrics and Gynecology, University of Nevada School of Medicine, Las Vegas, Nevada
Forest C. Garner, M.S.
- Fertility Center of Las Vegas, Las Vegas, Nevada
- Department of Obstetrics and Gynecology, University of Nevada School of Medicine, Las Vegas, Nevada
Martha Aguirre, Ph.D.
- Fertility Center of Las Vegas, Las Vegas, Nevada
Richard Ross, M.S.
- Fertility Center of Las Vegas, Las Vegas, Nevada

Received 20 July 2006; received in revised form 30 October 2006; accepted 16 November 2006. published online 12 February 2007.

In this retrospective study of 74 oocyte-donor IVF cycles, the rates of fertilization, implantation, clinical pregnancy, ongoing pregnancy, and early pregnancy loss were similar after an agonist or hCG trigger. These findings suggest that the agonist trigger is a viable alternative for oocyte donors with significant risk factors for ovarian hyperstimulation syndrome.