Fertility and Sterility
Volume 88, Issue 2 , Pages 379-382 , August 2007

Expression of various CDC25B isoforms in human spermatozoa

  • Yen-Ni Teng, Ph.D.

      Affiliations

    • Department of Biotechnology, Chia Nan University of Pharmacy and Science, National Cheng Kung University, College of Medicine, Tainan, Taiwan
    • ,
  • Chia-Ling Chung, M.Sc.

      Affiliations

    • Division of Genetics, Department of Obstetrics and Gynecology, National Cheng Kung University, College of Medicine, Tainan, Taiwan
    • ,
  • Yung-Ming Lin, M.D.

      Affiliations

    • Department of Urology, National Cheng Kung University, College of Medicine, Tainan, Taiwan
    • ,
  • Hsien-An Pan, M.D.

      Affiliations

    • Division of Genetics, Department of Obstetrics and Gynecology, National Cheng Kung University, College of Medicine, Tainan, Taiwan
    • ,
  • Rui-Wen Liao, M.Sc.

      Affiliations

    • Division of Genetics, Department of Obstetrics and Gynecology, National Cheng Kung University, College of Medicine, Tainan, Taiwan
    • ,
  • Pao-Lin Kuo, M.D.

      Affiliations

    • Division of Genetics, Department of Obstetrics and Gynecology, National Cheng Kung University, College of Medicine, Tainan, Taiwan
    • Corresponding Author InformationReprint requests: Pao-Lin Kuo, M.D., Division of Genetics, Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, 138 Sheng-Li Road, Tainan 704, Taiwan (FAX: 886-6-276-6185).

Received 23 May 2006 ,Revised 7 November 2006 ,Accepted 21 November 2006.

References 

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  2. Wickramasinghe D, Becker S, Ernst MK, Resnick JL, Centanni JM, Tessarollo L, et al. Two CDC25 homologs are differentially expressed during mouse development. Development. 1995;121:2047–2056
  3. Lincoln AJ, Wickramasinghe D, Stein P, Schultz RM, Palko ME, De Miguel MP, et al. Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation. Nat Genet. 2002;30:446–449
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  5. Cheng YS, Kuo PL, Teng YN, Kuo TY, Chung CL, Lin YH, et al. Association of spermatogenic failure with decreased CDC25A expression in infertile men. Hum Reprod. 2006;21:2346–2352
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  9. World Health Organization. In: Laboratory manual for the examination of human semen and semen–cervical mucus interaction. Cambridge: Cambridge University Press; 1992;p. 3–21
  10. Baldin V, Cans C, Superti-Furga G, Ducommun B. Alternative splicing of the human CDC25B tyrosine phosphatase (Possible implications for growth control?). Oncogene. 1997;14:2485–2495
  11. Lammer C, Wagerer S, Saffrich R, Mertens D, Ansorge W, Hoffmann I. The cdc25B phosphatase is essential for the G2/M phase transition in human cells. J Cell Sci. 1998;111:2445–2453
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  13. Solakidi S, Psarra AM, Nikolaropoulos S, Sekeris CE. Estrogen receptors alpha and beta (ERalpha and ERbeta) and androgen receptor (AR) in human sperm: localization of ERbeta and AR in mitochondria of the midpiece. Hum Reprod. 2005;20:3481–3487
  14. Visconti PE, Johnson LR, Oyaski M, Fornes M, Moss SB, Gerton GL, et al. Regulation, localization, and anchoring of protein kinase A subunits during mouse sperm capacitation. Dev Biol. 1997;192:351–363
  15. Tash JS, Bracho GE. Identification of phosphoproteins coupled to initiation of motility in live epididymal mouse sperm. Biochem Biophys Res Commun. 1998;251:557–563
  16. White DR, Aitken RJ. Relationship between calcium, cyclic AMP, ATP, and intracellular pH and the capacity of hamster spermatozoa to express hyperactivated motility. Gamete Res. 1989;22:163–177
  17. Ho HC, Granish KA, Suarez SS. Hyperactivated motility of bull sperm is triggered at the axoneme by Ca2+ and not cAMP. Dev Biol. 2002;250:208–217
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 Supported by grants NSC 94-2314-B-006-075, NSC 94-2314-B-006-076, and NSC 94-2320-B-041-012 from the National Science Council of Taiwan, Taipei, Taiwan.

PII: S0015-0282(06)04663-2

doi: 10.1016/j.fertnstert.2006.11.186

Fertility and Sterility
Volume 88, Issue 2 , Pages 379-382 , August 2007

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