Fertility and Sterility
Volume 88, Issue 3 , Pages 629-631 , September 2007

Ectopic pregnancy rates with frozen compared with fresh blastocyst transfer

  • Sunny H. Jun, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California
  • ,
  • Amin A. Milki, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California
    • Corresponding Author InformationReprint requests: Amin A. Milki, M.D., Stanford University Medical Center, 900 Welch Rd. Ste 350, Palo Alto, CA 94304 (FAX: 650-736-7036).

Received 24 May 2006 ,Revised 18 December 2006 ,Accepted 22 December 2006.

References 

  1. Marcus SF, Brinsden PR. Analysis of the incidence and risk factors associated with ectopic pregnancy following in-vitro fertilization and embryo transfer. Hum Reprod. 1995;10:199–203
  2. Strandell A, Thorburn J, Hamberger L. Risk factors for ectopic pregnancy in assisted reproduction. Fertil Steril. 1999;71:282–286
  3. Lesny P, Killick SR, Robinson J, Maguiness SD. Transcervical embryo transfer as a risk factor for ectopic pregnancy. Fertil Steril. 1999;72:305–309
  4. Russell JB. The etiology of ectopic pregnancy. Clin Obstet Gynecol. 1998;30:181–190
  5. Pyrgiotis E, Sultan KM, Neal GS, Liu HC, Grifo JA, Rosenwaks Z. Ectopic pregnancies after in vitro fertilization and embryo transfer. J Assist Reprod Genet. 1994;11:79–84
  6. Dubuisson JB, Aubriot FX, Mathieu L, Foulot H, Mandelbrot L, de Joliere JB. Risk factors for ectopic pregnancy in 556 pregnancies after in vitro fertilization: implications for preventive management. Fertil Steril. 1991;56:686–690
  7. Herman A, Ron-El R, Golan A, Weinraub Z, Bukovsky I, Caspi E. The role of tubal pathology and other parameters in ectopic pregnancies occurring in in vitro fertilization and embryo transfer. Fertil Steril. 1990;54:864–868
  8. Centers for Disease Control and Prevention . Assisted reproductive technology success rates: National Summary and Fertility Clinic Reports. Atlanta: CDC; 2003;
  9. Ng EHY, Yeung WSB, So WWK, Ho PC. An analysis of ectopic pregnancies following in vitro fertilization treatment in a 10-year period. J Obstet Gynaecol. 1998;18:359–364
  10. Kashyap S, Chung P, Kligman I, Rosenwaks Z. 7 year descriptive summary of ectopic pregnancies occurring after fresh and frozen IVF cycles. [abstract] Fertil Steril. 2002;78:S137
  11. Silva C, Trimarchi J, Keefe D, Frankfurter D. High incidence of ectopic pregnancy following frozen embryo transfer. [abstract] Fertil Steril. 2003;80:S178
  12. Check JH, Choe JK, Katsoff B, Krotec JW, Nazari A. Ectopic pregnancy is not more likely following fresh vs frozen embryo transfer. Clin Exp Obst Gyn. 2005;2:95–96
  13. Behr B, Gebhardt J, Lyon J, Milki AA. Factors relating to a successful cryopreserved blastocyst transfer program. Fertil Steril. 2002;77:697–699
  14. Steptoe PC, Edwards RG. Reimplantation of a human embryo with subsequent tubal pregnancy. Lancet. 1976;1:880–882
  15. Milki AA, Jun SH. Ectopic pregnancy rates with day 3 versus day 5 embryo transfer: a retrospective analysis. BMC Pregnancy Childbirth. 2003;3:7
  16. Jun SH, Milki AA. Assisted hatching is associated with a higher ectopic pregnancy rate. Fertil Steril. 2004;81:1701–1703
  17. Fanchin R, Ayoubi JM, Righini C, Olivennes F, Schonauer LM, Frydman R. Uterine contractility decreases at the time of blastocyst transfers. Hum Reprod. 2001;16:1115–1119
  18. Fanchin R, Righini C, de Ziegler D, Olivennes F, Ledee N, Frydman R. Effects of vaginal progesterone administration on uterine contractility at the time of embryo transfer. Fertil Steril. 2001;75:1136–1140

PII: S0015-0282(07)00030-1

doi: 10.1016/j.fertnstert.2006.12.005

Fertility and Sterility
Volume 88, Issue 3 , Pages 629-631 , September 2007