Fertility and Sterility
Volume 88, Issue 4 , Pages 785-788 , October 2007

Estrogen receptor β gene +1730 G/A polymorphism in women with endometriosis

  • Gyoung Hoon Lee, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • ,
  • Sung Hoon Kim, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
    • ,
  • Young Min Choi, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • Corresponding Author InformationReprint requests: Young Min Choi, M.D., Department of Obstetrics and Gynecology, The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, 28 Yungun-dong, Chongno-ku, Seoul 110-744, Korea (FAX: 82-2-762-3599).
    • ,
  • Chang Suk Suh, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • ,
  • Jung Gu Kim, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • ,
  • Shin Yong Moon, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea
    • The Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University College of Medicine, Seoul, Korea

Received 22 July 2006 ,Revised 5 December 2006 ,Accepted 5 December 2006.

References 

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  2. Howell RJ, Dowsett M, Edmonds DK. Oestrogen and progesterone receptors in endometriosis: heterogeneity of different sites. Hum Reprod. 1994;9:1752–1758
  3. Jones RK, Bulmer JN, Searle RF. Immunohistochemical characterization of proliferation, oestrogen receptor and progesterone receptor expression in endometriosis: comparison of eutopic and ectopic endometrium with normal cycling endometrium. Hum Reprod. 1995;10:3272–3279
  4. Rey JM, Pujol P, Dechaud H, Edouard E, Hedon B, Maudelonde T. Expression of oestrogen receptor-alpha splicing variants and oestrogen receptor-beta in endometrium of infertile patients. Mol Hum Reprod. 1998;4:641–647
  5. Fujishita A, Nakane PK, Koji T, Masuzaki H, Chavez RO, Yamabe T, et al. Expression of estrogen and progesterone receptors in endometrium and peritoneal endometriosis: an immunohistochemical and in situ hybridization study. Fertil Steril. 1997;67:856–864
  6. Kitawaki J, Noguchi T, Amatsu T, Maeda K, Tsukamoto K, Yamamoto T, et al. Expression of aromatase cytochrome P450 protein and messenger ribonucleic acid in human endometriotic and adenomyotic tissues but not in normal endometrium. Biol Reprod. 1997;57:514–519
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  11. Kim SH, Choi YM, Jun JK, Kim SH, Kim JG, Moon SY. Estrogen receptor dinucleotide repeat polymorphism is associated with minimal or mild endometriosis. Fertil Steril. 2005;84:774–777
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  13. Revised American Society for Reproductive Medicine classification of endometriosis: 1996. Fertil Steril. 1997;67:817–821
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  15. Westberg L, Hakansson A, Melke J, Shahabi HN, Nilsson S, Buervenich S, et al. Association between the estrogen receptor beta gene and age of onset of Parkinson's disease. Psychoneuroendocrinology. 2004;29:993–998
  16. Pirskanen M, Hiltunen M, Mannermaa A, Helisalmi S, Lehtovirta M, Hunninen T, et al. Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women. Eur J Hum Genet. 2005;13:1000–1006
  17. Aschim EL, Giwercman A, Stahl O, Eberhard J, Cwikiel M, Nordenskjold A, et al. The RsaI polymorphism in the ER{beta} gene is associated with male infertility. J Clin Endocrinol Metab. 2005;90:5343–5348
  18. Zondervan KT, Cardon LR, Kennedy SH. What makes a good case-control study? Design issues for complex traits such as endometriosis. Hum Reprod. 2002;17:1415–1423
  19. Salanti G, Sanderson S, Higgins JP. Obstacles and opportunities in meta-analysis of genetic association studies. Genet Med. 2005;7:13–20
  20. Hadfield RM, Manek S, Weeks DE, Mardon HJ, Barlow DH, Kennedy SH OXEGENE Collaborative Group. Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1. Mol Hum Reprod. 2001;7:1073–1078

 Supported by grant (01-PJ10-PG6-01GN13-0002) from the Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea.

PII: S0015-0282(07)00061-1

doi: 10.1016/j.fertnstert.2006.12.032

Fertility and Sterility
Volume 88, Issue 4 , Pages 785-788 , October 2007

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