Fertility and Sterility
Volume 89, Issue 6 , Pages 1766-1770, June 2008

Preconception folic acid treatment affects the microenvironment of the maturing oocyte in humans

  • Jolanda C. Boxmeer, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • ,
  • R. Montserrate Brouns, M.Sc.

      Affiliations

    • Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • ,
  • Jan Lindemans, Ph.D.

      Affiliations

    • Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • ,
  • Eric A.P. Steegers, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • ,
  • Elena Martini, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • ,
  • Nick S. Macklon, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • Department of Reproductive Medicine and Gynecology, University Medical Center, Utrecht, The Netherlands
    • ,
  • Régine P.M. Steegers-Theunissen, Ph.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • Department of Epidemiology and Biostatistics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • Department of Pediatric Cardiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • Department of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    • Corresponding Author InformationReprint requests: Régine P.M. Steegers-Theunissen, M.D., Ph.D., Associate Professor in Reproductive Epidemiology, Erasmus MC, University Medical Center, Department of Obstetrics and Gynecology/Division of Obstetrics and Prenatal Medicine, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands (FAX: 31-10-4636815).

Received 18 April 2007; received in revised form 15 June 2007; accepted 15 June 2007. published online 08 October 2007.

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PII: S0015-0282(07)01379-9

doi:10.1016/j.fertnstert.2007.06.036

Fertility and Sterility
Volume 89, Issue 6 , Pages 1766-1770, June 2008

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