Fertility and Sterility
Volume 89, Issue 5 , Pages 1240-1244 , May 2008

Interpregnancy weight gain and the male-to-female sex ratio of the second pregnancy: a population-based cohort study

  • Eduardo Villamor, M.D., DrPH.

      Affiliations

    • Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    • Corresponding Author InformationReprint requests: E. Villamor, Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115 (FAX: 617-432-2435).
    • ,
  • Pär Sparén, Ph.D.

      Affiliations

    • Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    • ,
  • Sven Cnattingius, M.D., Ph.D.

      Affiliations

    • Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Received 27 June 2007 ,Revised 7 July 2007 ,Accepted 25 July 2007.

References 

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  2. Davis DL, Gottlieb MB, Stampnitzky JR. Reduced ratio of male to female births in several industrial countries: a sentinel health indicator?. JAMA. 1998;279:1018–1023
  3. Fukuda M, Fukuda K, Shimizu T, Andersen CY, Byskov AG. Parental periconceptional smoking and male: female ratio of newborn infants. Lancet. 2002;359:1407–1408
  4. Beratis NG, Asimacopoulou A, Varvarigou A. Association of secondary sex ratio with smoking and parity. Fertil Steril. Published online May 19, 2007.
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  6. Rosenfeld CS, Roberts RM. Maternal diet and other factors affecting offspring sex ratio: a review. Biol Reprod. 2004;71:1063–1070
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  8. Stein AD, Zybert PA, Lumey LH. Acute undernutrition is not associated with excess of females at birth in humans: the Dutch hunger winter. Proc Biol Sci. 2004;271(Suppl 4):S138–S141
  9. Andersson R, Bergstrom S. Is maternal malnutrition associated with a low sex ratio at birth?. Hum Biol. 1998;70:1101–1106
  10. Gibson MA, Mace R. Strong mothers bear more sons in rural Ethiopia. Proc Biol Sci. 2003;270(Suppl 1):S108–S109
  11. Stein AD, Barnett PG, Sellen DW. Maternal undernutrition and the sex ratio at birth in Ethiopia: evidence from a national sample. Proc Biol Sci. 2004;271(Suppl 3):S37–S39
  12. Bittles AH, McHugh JJ, Makov E. The Irish famine and its sequel: population structure changes in the Ards Peninsula, Co. Down, 1841–1911. Ann Hum Biol. 1986;13:473–487
  13. Caughey AB. Obesity, weight loss, and pregnancy outcomes. Lancet. 2006;368:1136–1138
  14. Rochelson B, Vohra N, Darvishzadeh J, Pagano M. Low prepregnancy ideal weight:height ratio in women with hyperemesis gravidarum. J Reprod Med. 2003;48:422–424
  15. Askling J, Erlandsson G, Kaijser M, Akre O, Ekbom A. Sickness in pregnancy and sex of child. Lancet. 1999;354:2053
  16. Sharpe RM, Skakkebaek NE. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?. Lancet. 1993;341:1392–1395

 Supported by grants from the Karolinska Institutet.

PII: S0015-0282(07)03016-6

doi: 10.1016/j.fertnstert.2007.07.1371

Fertility and Sterility
Volume 89, Issue 5 , Pages 1240-1244 , May 2008

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