Successful pregnancy outcome after in vitro fertilization in a pancreas-kidney recipient

Objective

To describe the first case of IVF pregnancy in a pancreas-kidney recipient.

Design

Case report.

Setting

Reproductive Medicine Department, Hôpital Edouard Herriot, Lyon, France.

Intervention(s)

In vitro fertilization in a pancreas-kidney recipient.

Patient(s)

A 39 year-old nulliparous woman, with primary infertility and a history of pancreas-kidney transplant at 29 years of age.

Main Outcome Measure(s)

Multidisciplinary agreement for the couple to be managed by IVF. Follow-up of pregnancy and delivery.

Result(s)

Singleton IVF pregnancy in a pancreas-kidney recipient, maintained up to 34 weeks. Cesarian delivery ahead of labor. No severe maternal or fetal complications. Live birth. Normal postpartum renal function and glycemia.

Conclusion(s)

An IVF pregnancy is feasible in a pancreas-kidney recipient. Such treatment should follow agreement by all the medical teams following the patient. Pregnancy in a pancreas-kidney recipient is at-risk, requiring close monitoring.

Key Words: IVF-ET, pancreas-kidney recipient, pregnancy, multidisciplinary team