Fertility and Sterility
Volume 89, Issue 2 , Pages 278-280, February 2008

Aromatase inhibitors for infertility in polycystic ovary syndrome. The beginning or the end of a new era?

  • Nikolaos P. Polyzos, M.D.

      Affiliations

    • PACMeR (PanHellenic Association for Continual Medical Research), Sections of Obstetrics and Gynaecology and Public Health, Athens, Greece
    • Corresponding Author InformationReprint requests: Nikolaos P. Polyzos, M.D., Panhellenic Association for Continual Medical Research (PACMeR) Section of Obstetrics & Gynaecology, 28 Metamorfoseos St, 38333, Volos, Greece (FAX: +302421038852).
    • ,
  • Maria Tsappi, M.D.

      Affiliations

    • PACMeR (PanHellenic Association for Continual Medical Research), Sections of Obstetrics and Gynaecology and Public Health, Athens, Greece
    • ,
  • Davide Mauri, M.D.

      Affiliations

    • PACMeR (PanHellenic Association for Continual Medical Research), Sections of Obstetrics and Gynaecology and Public Health, Athens, Greece
    • ,
  • Vedat Atay, M.D.

      Affiliations

    • Obstetrics and Gynaecology Department, GATA Haydarpasa Training Hospital, Istanbul, Turkey
    • ,
  • Ivan Cortinovis, Ph.D.

      Affiliations

    • Istituto di Statistica Medica e Biometria, University of Milan, Milan, Italy
    • ,
  • Giovanni Casazza, Ph.D.

      Affiliations

    • Istituto di Statistica Medica e Biometria, University of Milan, Milan, Italy

Received 1 July 2007; received in revised form 1 October 2007; accepted 10 October 2007.

A meta-analysis of four trials showed significant advantage in pregnancy and delivery rates with aromatase inhibitors compared with CC in women with PCOS. A recent randomized trial demonstrated no clear benefit.

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 Presented at the 5th World Congress on Ovulation Induction, Rome, Italy, September 13–15, 2007.

PII: S0015-0282(07)03869-1

doi:10.1016/j.fertnstert.2007.10.016

Fertility and Sterility
Volume 89, Issue 2 , Pages 278-280, February 2008

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