The effect of selecting oocytes for insemination and transferring all resultant embryos without selection on outcomes of assisted reproduction
Objective
To evaluate the effect of selecting three best oocytes for insemination and transfer of all resultant embryos on outcomes of assisted reproductive technologies (ART).
Study Design
Comparative study.
Setting
The Center of Reproductive Medicine, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.
Patient(s)
Women undergoing ART during the period March 10, 2004 to March 9, 2006.
Intervention(s)
Comparing outcomes of ART following transfers of 3 “excellent” (n = 267) embryos and cycles in which none of the embryos was considered “excellent quality” (n = 176).
Main Outcome Measure(s)
Rates of fertilization, pregnancy, “take-home baby,” and multiple pregnancies.
Results
The average number of retrieved oocytes and the average number of inseminated oocytes of good quality were similar in both groups. Intracytoplasmic sperm injection was performed four to five times more often in cycles without “excellent quality” irrespective of the patient's age (odds ratio 4.6, 95% confidence interval 3.0, 7.1). The two groups had similar rates of implantation, total pregnancies/ET, clinical intrauterine pregnancy, singleton and multiple births, and “take-home” baby rate. This similarity persisted irrespective of the patient's age.
Conclusion(s)
The selection of oocytes for insemination and transfer of all available embryos irrespective of their quality did not change outcomes of ART.
Key Words: Oocyte quality, embryo quality, in vitro fertilization, intracytoplasmic sperm injection
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The authors hereby state that no conflict of interest exists and there was no commercial/financial support.
Reprints will not be available
PII: S0015-0282(07)03975-1
doi:10.1016/j.fertnstert.2007.11.010
© 2009 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

