Fertility and Sterility
Volume 91, Issue 1 , Pages 56-61, January 2009

Common 677C→T mutation of the 5,10-methylenetetrahydrofolate reductase gene affects follicular estradiol synthesis

  • Stephanie Hecht

      Affiliations

    • Department of Obstetrics and Gynecology, Division of Endocrinology and Reproductive Medicine, Grosshadern, Ludwig Maximilians-University, Munich, Germany
  • ,
  • Roman Pavlik

      Affiliations

    • Department of Obstetrics and Gynecology, Division of Endocrinology and Reproductive Medicine, Grosshadern, Ludwig Maximilians-University, Munich, Germany
  • ,
  • Peter Lohse, M.D.

      Affiliations

    • Department of Clinical Chemistry, Grosshadern, Ludwig Maximilians-University, Munich, Germany
  • ,
  • Ulrich Noss, M.D.

      Affiliations

    • Centre for Reproductive Medicine, Munich, Germany
  • ,
  • Klaus Friese, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Division of Endocrinology and Reproductive Medicine, Grosshadern, Ludwig Maximilians-University, Munich, Germany
  • ,
  • Christian J. Thaler, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Division of Endocrinology and Reproductive Medicine, Grosshadern, Ludwig Maximilians-University, Munich, Germany
    • Corresponding Author InformationReprint requests: Christian J. Thaler, M.D., Department of Obstetrics and Gynecology, Division of Endocrinology and Reproductive Medicine, Grosshadern, Ludwig-Maximilians-University, Marchioninistrasse 15, D-81377 Munich, Germany (FAX: 49-89-7095-7588).

Received 14 March 2007; received in revised form 5 November 2007; accepted 5 November 2007. published online 13 February 2008.

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 Authors S.H. and R.P. contributed equally to the work and both should be considered to be the first author.

 Supported by the Department of Obstetrics and Gynecology, Grosshadern, Ludwig-Maximilians-University, Munich, Germany.

 Presented at the 56th National Congress of Gynecology and Obstetrics, Berlin, Germany, September 19–22, 2006.

PII: S0015-0282(07)03976-3

doi:10.1016/j.fertnstert.2007.11.011

Fertility and Sterility
Volume 91, Issue 1 , Pages 56-61, January 2009