Fertility and Sterility
Volume 91, Issue 1 , Pages 28-31 , January 2009

Early termination of pregnancy by single-dose 800 μg misoprostol compared with surgical evacuation

  • Sudha Prasad, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Maulana Azad Medical College, New Delhi, India
    • Corresponding Author InformationReprint requests: Sudha Prasad, M.D., Department of Obstetrics and Gynecology, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi–110 002, India.
  • ,
  • Ashok Kumar, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Maulana Azad Medical College, New Delhi, India
  • ,
  • Aabha Divya, MBBS

      Affiliations

    • All India Institute of Medical Sciences, New Delhi, India

Received 23 July 2007 ,Revised 12 November 2007 ,Accepted 12 November 2007.

References 

  1. Ngai PC, Wong Liv KL, Lee SW. Vaginal misoprostol compared with oral misoprostol in the termination of second trimester pregnancy. Obstet Gynecol. 1997;90:735–738
  2. Koopersmith TB, Mishell DR. The use of misoprostol for termination of early pregnancy by the vaginal route. Contraception. 1996;53:237–242
  3. Bungalow F, James L, Usfa M, Maria E, Bique C. Evaluation of effectiveness of vaginal misoprostol to induce first trimester abortion. Contraception. 1996;53:243–246
  4. Tang OS, Miao BY, Lee SWH, Ho PC. Pilot study on the use of repeated doses of sublingual misoprostol in termination of pregnancy up to 12 weeks gestation: efficacy and acceptability. Hum Reprod. 2002;17:654–658
  5. Kulier R, Gulmezoglu AM, Hofmeyur GJ, Cheng LN, Campana A. Medical methods for first trimester abortion. Cochrane Database Syst Rev. 2004;2:CD002855
  6. Ziaei S, Zakeri M, Kazemnejad A. Randomized controlled trial of vitamin E in the treatment of primary dysmenorrhoea. BJOG. 2005;112:466–469
  7. Carbonell JLL, Varela L, Velazco A, Fernandez C. The use of misoprostol for termination of early pregnancy. Contraception. 1997;55:165–168
  8. Esteve Carbonell JLL, Varela L, Velazco A, Tanda R, Cabezas E, Sanchez C. Early abortion with 800 micrograms of misoprostol by the vaginal route. Contraception. 1999;59:219–225
  9. Bugalho A, Bique C, Almeida L, Faundes A. The effectiveness of intravaginal misoprostol (Cytotec) in inducing abortion after eleven weeks of pregnancy. Stud Fam Plann. 1993;24:319–323
  10. Jain JK, Dutton C, Harwood B, Karen RM, Daniel RM. A prospective randomized, double-blinded, placebo-controlled trial comparing mifepristone and vaginal misoprostol to vaginal misoprostol alone for an elective termination of early pregnancy. Hum Reprod. 2002;17:1477–1482
  11. Bugalho A, Mocumbi S, Faundes A, David E. Termination of pregnancy <6 weeks gestation with a single dose of 800 micrograms of vaginal misoprostol. Contraception. 2000;61:47–50
  12. Zikopoulos KA, Papanikolaou EG, Kalantaridou SN, Tsanadis GD, Plachouras NI, Dalkalitsis NA, et al. Early pregnancy termination with vaginal misoprostol before and after 42 days gestation. Hum Reprod. 2002;17:3079–3083
  13. Wiebe ER. Choosing between surgical abortion and medical abortion induced with methotrexate and misoprostol. Contraception. 1997;55:67–71

 S.P. has nothing to disclose. A.K. has nothing to disclose. A.D. has nothing to disclose.

PII: S0015-0282(07)04093-9

doi: 10.1016/j.fertnstert.2007.11.028

Fertility and Sterility
Volume 91, Issue 1 , Pages 28-31 , January 2009