Fertility and Sterility
Volume 91, Issue 1 , Pages e5-e6 , January 2009

CAG repeat polymorphism in the androgen receptor: a study on the effect of different numbers of repeats using Gene Ontology technique

  • Viroj Wiwanitkit, M.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Viroj Wiwanitkit, M.D., Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 10330 (FAX: 662-2524636).

Received 7 August 2007 ,Revised 14 November 2007 ,Accepted 14 November 2007.

References 

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  4. Rajender S, Singh L, Thangaraj K. Phenotypic heterogeneity of mutations in androgen receptor gene. Asian J Androl. 2007;9:147–179
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  8. Marcelli M, Tilley WD, Wilson CM, Griffin JE, Wilson JD, McPhaul MJ. Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance. Mol Endocrinol. 1990;4:1105–1116
  9. De Abreu FB, Pirolo LJ, Canevari Rde A, Rosa FE, Moraes Neto FA, Caldeira JR, et al. Shorter CAG repeat in the AR gene is associated with atypical hyperplasia and breast carcinoma. Anticancer Res. 2007;27:1199–1205
  10. Schildkraut JM, Murphy SK, Palmieri RT, Iversen E, Moorman PG, Huang Z, et al. Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2007;16:473–480
  11. Sieh W, Edwards KL, Fitzpatrick AL, Srinouanprachanh SL, Farin FM, Monks SA, et al. Genetic susceptibility to prostate cancer: prostate-specific antigen and its interaction with the androgen receptor (United States). Cancer Causes Control. 2006;17:187–197
  12. Kalita J, Misra UK, Mishra DK, Thangaraj K, Mittal RD, Mittal BR. Nonprogressive juvenile-onset spinal muscular atrophy: a clinico-radiological and CAG repeat study of androgen receptor gene. J Neurol Sci. 2007;252:24–28

PII: S0015-0282(07)04100-3

doi: 10.1016/j.fertnstert.2007.11.035

Fertility and Sterility
Volume 91, Issue 1 , Pages e5-e6 , January 2009

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