Fertility and Sterility
Volume 91, Issue 2 , Pages 639-643 , February 2009

Etiology of sperm immunity in women

  • Gary N. Clarke, D.Sc.

      Affiliations

    • Corresponding Author InformationReprint requests: Gary N. Clarke, D.Sc., Andrology Unit, Royal Women's Hospital, 321 Cardigan Street, Carlton, Melbourne, Victoria 3053, Australia (FAX: 61-3-93442691).

Received 1 November 2007 ,Revised 15 November 2007 ,Accepted 15 November 2007.

References 

  1. Meaker S. Some aspects of the problem of sterility. Boston Med Surg J. 1922;187:535–539
  2. Katsh S. Immunology, fertility, and infertility: a historical survey. Am J Obstet Gynecol. 1959;77:946–956
  3. Baskin MJ. Temporary sterilization by the injection of human spermatozoa. Am J Obstet Gynecol. 1932;24:892–897
  4. Franklin RR, Dukes CD. Further studies on sperm-agglutinating antibody and unexplained infertility. JAMA. 1964;190:682–683
  5. Clarke GN. Sperm antibodies and human fertilization. Am J Reprod Immunol Microbiol. 1988;17:65–71
  6. Marshburn PB, Kutteh WH. The role of antisperm antibodies in infertility. Fertil Steril. 1994;61:799–811
  7. Bronson RA. Antisperm antibodies: a critical evaluation and clinical guidelines. J Reprod Immunol. 1999;45:159–183
  8. Chamley LW, Clarke GN. Antisperm antibodies and conception. Sem Immunopathol. 2007;29:169–184
  9. Anderson DJ. The importance of mucosal immunology to problems in human reproduction. J Reprod Immunol. 1996;31:3–19
  10. Ingerslev HJ, Moller NP, Jager S, Kremer J. Immunoglobulin class of sperm antibodies in cervical mucus from infertile women. Am J Reprod Immunol. 1982;2:296–300
  11. Kremer J, Jager S. The significance of antisperm antibodies for sperm-cervical mucus interaction. Hum Reprod. 1992;7:781–784
  12. Menge AC, Medley NE, Mangione CM, Dietrich JW. The incidence and influence of antisperm antibodies in infertile human couples on sperm-cervical mucus interactions and subsequent fertility. Fertil Steril. 1982;38:439–446
  13. Cantuaria AA. Sperm immobilizing antibodies in the serum and cervicovaginal secretions of infertile and normal women. Br J Obstet Gynaecol. 1977;84:865–868
  14. Clarke GN, Stojanoff A, Cauchi MN, McBain JC, Speirs AL, Johnston WI. Detection of antispermatozoal antibodies of IgA class in cervical mucus. Am J Reprod Immunol. 1984;5:61–65
  15. Clarke GN, Lopata A, Johnston WI. Effect of sperm antibodies in females on human in vitro fertilization. Fertil Steril. 1986;46:435–441
  16. Clarke GN, Hyne RV, du Plessis Y, Johnston WI. Sperm antibodies and human in vitro fertilization. Fertil Steril. 1988;49:1018–1025
  17. Yeh WR, Acosta AA, Seltman HJ, Doncel G. Impact of immunoglobulin isotype and sperm surface location of antisperm antibodies on fertilization in vitro in the human. Fertil Steril. 1995;63:1287–1292
  18. Ford WC, Williams KM, McLaughlin EA, Harrison S, Ray B, Hull MG. The indirect immunobead test for seminal antisperm antibodies and fertilization rates at in-vitro fertilization. Hum Reprod. 1996;11:1418–1422
  19. de Almeida M, Gazagne I, Jeulin C, Herry M, Belaisch-Allart J, Frydman R, et al. In-vitro processing of sperm with autoantibodies and in-vitro fertilization results. Hum Reprod. 1989;4:49–53
  20. Witkin SS, Chaudhry A. Relationship between circulating antisperm antibodies in women and autoantibodies on the ejaculated sperm of their partners. Am J Obstet Gynecol. 1989;161:900–903
  21. Witkin SS, Vogel-Roccuzzo R, David SS, Berkeley A, Goldstein M, Graf M. Heterogeneity of antigenic determinants on human spermatozoa: relevance to antisperm antibody testing in infertile couples. Am J Obstet Gynecol. 1988;159:1228–1231
  22. Sarkar S. Carbohydrate antigens of human sperm and autoimmune induction of infertility. J Reprod Med. 1974;13:93–99
  23. Blum M, Pery J, Blum I. Antisperm antibodies in young oral contraceptive users. Adv Contracept. 1989;5:41–46
  24. Cunningham DS, Fulgham DL, Rayl DL, Hansen KA, Alexander NJ. Antisperm antibodies to sperm surface antigens in women with genital tract infection. Am J Obstet Gynecol. 1991;164:791–796
  25. Eggert-Kruse W, Rohr G, Probst S, Rusu R, Hund M, Demirakca T, et al. Antisperm antibodies and microorganisms in genital secretions—a clinically significant relationship?. Andrologia. 1998;30(Suppl 1):61–71
  26. Witkin SS. Production of interferon gamma by lymphocytes exposed to antibody-coated spermatozoa: a mechanism for sperm antibody production in females. Fertil Steril. 1988;50:498–502
  27. Jerne NK. Towards a network theory of the immune system. Ann Immunol (Paris). 1974;125C:373–389
  28. Monroe JG, Greene MI. Anti-idiotypic antibodies and disease. Immunol Invest. 1986;15:263–286
  29. Carron CP, Jarvis HW, Saling PM. Characterization of antibodies to idiotypic determinants of monoclonal anti-sperm antibodies. Biol Reprod. 1988;38:1093–1103
  30. Carron CP, Mathias A, Saling PM. Anti-idiotype antibodies prevent antibody binding to mouse sperm and antibody-mediated inhibition of fertilization. Biol Reprod. 1989;41:153–162
  31. Kuo CY, Sun P, Lee CY. Sperm antibodies induced by anti-idiotype antibodies: a strategy in development of immunocontraceptive vaccines. J Reprod Immunol. 1988;13:193–209
  32. el-Roeiy A, Valesini G, Friberg J, Shoenfeld Y, Kennedy RC, Tincani A, et al. Autoantibodies and common idiotypes in men and women with sperm antibodies. Am J Obstet Gynecol. 1988;158:596–603
  33. Robertson SA, Bromfield JJ, Tremellen KP. Seminal “priming” for protection from pre-eclampsia—a unifying hypothesis. J Reprod Immunol. 2003;59:253–265

PII: S0015-0282(07)04109-X

doi: 10.1016/j.fertnstert.2007.11.045

Fertility and Sterility
Volume 91, Issue 2 , Pages 639-643 , February 2009

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