Fertility and Sterility
Volume 90, Issue 1 , Pages 77-83, July 2008

Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study

  • Richard Scott, M.D.

      Affiliations

    • Reproductive Medicine Associates of New Jersey, Morristown, New Jersey; Department of Obstetrics, Gynecology, and Reproductive Sciences, UMDNJ–Robert Wood Johnson Medical School, New Brunswick, New Jersey
    • ,
  • Emre Seli, M.D.

      Affiliations

    • Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Kathy Miller, B.S.

      Affiliations

    • Reproductive Medicine Associates of New Jersey, Morristown, New Jersey; Department of Obstetrics, Gynecology, and Reproductive Sciences, UMDNJ–Robert Wood Johnson Medical School, New Brunswick, New Jersey
    • ,
  • Denny Sakkas, Ph.D.

      Affiliations

    • Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Katherine Scott, B.S.

      Affiliations

    • Reproductive Medicine Associates of New Jersey, Morristown, New Jersey; Department of Obstetrics, Gynecology, and Reproductive Sciences, UMDNJ–Robert Wood Johnson Medical School, New Brunswick, New Jersey
    • ,
  • David H. Burns, Ph.D.

      Affiliations

    • Department of Chemistry, McGill University, Montreal, Quebec, Canada
    • Corresponding Author InformationReprint requests: David H. Burns, Ph.D., Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal QC H3A 2K6, Canada (FAX: 514-398-3797).

Received 11 February 2007; received in revised form 20 November 2007; accepted 20 November 2007. published online 18 February 2008.

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 One of the authors, D.B., has an equity interest in the company developing this technology for clinical application (Molecular Biometrics, LLC). Three authors, R.S., E.S., and D.S., serve on a scientific advisory board of Molecular Biometrics.

PII: S0015-0282(07)04123-4

doi:10.1016/j.fertnstert.2007.11.058

Fertility and Sterility
Volume 90, Issue 1 , Pages 77-83, July 2008

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