Fertility and Sterility
Volume 91, Issue 3 , Pages 893-899 , March 2009

Sildenafil citrate (Viagra) impairs fertilization and early embryo development in mice

  • David R.J. Glenn, M.R.C.O.G.

      Affiliations

    • Obstetrics and Gynaecology, Institute of Clinical Science, School of Medicine, Belfast, United Kingdom
    • ,
  • Neil McClure, F.R.C.O.G.

      Affiliations

    • Obstetrics and Gynaecology, Institute of Clinical Science, School of Medicine, Belfast, United Kingdom
    • ,
  • S. Louise Cosby, Ph.D., F.R.C.Path.

      Affiliations

    • Division of Infection and Immunity, School of Biomedical Science, Queen's University, Belfast, United Kingdom
    • ,
  • Michael Stevenson, B.Sc.

      Affiliations

    • Obstetrics and Gynaecology, Institute of Clinical Science, School of Medicine, Belfast, United Kingdom
    • ,
  • Sheena E.M. Lewis, Ph.D.

      Affiliations

    • Obstetrics and Gynaecology, Institute of Clinical Science, School of Medicine, Belfast, United Kingdom
    • Corresponding Author InformationReprint requests: Sheena E. M. Lewis, Obstetrics & Gynaecology, Institute of Clinical Science, Grosvenor Road, Belfast, United Kingdom (FAX: 44 2890328247).

Received 31 August 2007 ,Revised 5 December 2007 ,Accepted 5 December 2007.

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 D.R.J.G. has nothing to disclose. N.McC. has nothing to disclose. S.L.C. has nothing to disclose. M.S. has nothing to disclose. S.E.M.L. has nothing to disclose.

 Presented at the British Fertility Society Spring meeting, Cheltenham, United Kingdom, April 2004.

 Dr. Glenn was supported with a Royal Clinical Research Fellowship from the Royal Maternity Hospital.

PII: S0015-0282(07)04196-9

doi: 10.1016/j.fertnstert.2007.12.014

Fertility and Sterility
Volume 91, Issue 3 , Pages 893-899 , March 2009

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