Received 3 December 2007; received in revised form 7 January 2008; accepted 7 January 2008. published online 06 March 2008.
Objective
To report a case of successful use of a transdermal contraceptive in a patient with hereditary angioedema.
Design
Case report.
Setting
University medical center.
Patient(s)
A patient who had used oral contraceptives contracted SC and submucosal tumefaction every 1 or 2 months. She was diagnosed with type I hereditary angioedema. It was determined that she was complement C4 deficient and C1-inhibitor quantitative deficient but functional C1-inhibitor normal. After she was diagnosed, the use of oral contraceptives was contraindicated.
Intervention(s)
Oral contraceptives were suspended, and a hormonal transdermal contraceptive was started.
Main Outcome Measure(s)
The absence of symptoms after 26 months using a transdermal contraceptive.
Result(s)
After 26 months of using this treatment, the patient has not experienced any symptoms of the hereditary angioedema.
Conclusion(s)
The use of hormonal contraceptives transdermally can be an alternative in patients with hereditary angioedema.
Obstetrics and Gynaecology Department, School of Medicine, Health Sciences Faculty, Andres Bello University, Santiago, Chile
Reprint requests: Pablo I. Sanhueza, M.D., Obstetrics and Gynaecology Department, School of Medicine, Health Sciences Faculty, Andres Bello University, Sazie 2212, Santiago, Chile (FAX: 5626618333).
ABSTRACT