Fertility and Sterility
Volume 91, Issue 4, Supplement , Pages 1299-1302, April 2009

Ovarian follicular volume and follicular surface area are better indicators of follicular growth and maturation, respectively, than is follicular diameter

  • Yalcin Yavas, Ph.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Yalcin Yavas, Ph.D., Florida Institute for Reproductive Sciences and Technologies, 2300 N. Commerce Parkway, Suite 313, Weston, Florida, 33326-3257 (FAX: 954-217-3462).
  • ,
  • Minna R. Selub, M.D.

Florida Institute for Reproductive Sciences and Technologies, Weston, Florida

Received 22 February 2005; received in revised form 11 January 2008; accepted 11 January 2008. published online 18 March 2008.

Because ovarian follicular growth occurs in three dimensions, and because follicular maturation (increased E2) is a result of an increase in the three-dimensional follicular surface area where testosterone (E2 precursor)–producing theca interna cells are located, the three-dimensional follicular volume and the three-dimensional follicular surface area describe the three-dimensional follicular growth and maturation, respectively, more accurately than does the two-dimensional follicular diameter alone. Therefore, we present a mathematical model that describes the relationship of the two-dimensional follicular diameter, the three-dimensional follicular volume, and the three-dimensional follicular surface area to the three-dimensional follicular growth and maturation.

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 Y.Y. has nothing to disclose. M.R.S. has nothing to disclose.

 Presented at the 62nd annual meeting of the American Society for Reproductive Medicine, New Orleans, Louisiana, October 21–25, 2006.

PII: S0015-0282(08)00145-3

doi:10.1016/j.fertnstert.2008.01.050

Fertility and Sterility
Volume 91, Issue 4, Supplement , Pages 1299-1302, April 2009