Maternal virilization due to luteoma associated with delayed lactation
Received 14 November 2007; received in revised form 11 January 2008; accepted 14 January 2008. published online 17 July 2008.
Objective
To report on a patient with virilization during pregnancy who experienced delayed lactation secondary to elevated maternal androgens.
Design
Case report and review of the literature.
Setting
University hospital.
Patient(s)
A 32-year-old pregnant woman presented with virilization at 32 weeks' gestation.
Intervention(s)
Laboratory evaluation, ultrasound examination, magnetic resonance imaging, cesarean section for fetal indication, nipple stimulation to facilitate lactation.
Main Outcome Measure(s)
Case report.
Result(s)
Postpartum normalization of serum T levels and patient ability to breastfeed exclusively after delayed initiation of lactation.
Conclusion(s)
Maternal virilization during pregnancy is rare and is often due to androgen-secreting tumors that are benign. Therefore, careful evaluation of these patients is important to avoid inadvertent oophorectomy.
aDepartment of Obstetrics and Gynecology, University of Cincinnati Medical Center, Cincinnati, Ohio
bDepartment of Obstetrics and Gynecology, Women and Infants Hospital, Brown University, Providence, Rhode Island
Reprint requests: Stephanie K. Dahl, M.D., Department of Obstetrics and Gynecology, The University of North Dakota School of Medicine, 1919 N. Elm Street, Fargo, ND 58102 (FAX: 701-234-2783).
ABSTRACT