Fertility and Sterility
Volume 90, Issue 5 , Pages 2006.e17-2006.e19, November 2008

Maternal virilization due to luteoma associated with delayed lactation

  • Stephanie K. Dahl, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Cincinnati Medical Center, Cincinnati, Ohio
    • Corresponding Author InformationReprint requests: Stephanie K. Dahl, M.D., Department of Obstetrics and Gynecology, The University of North Dakota School of Medicine, 1919 N. Elm Street, Fargo, ND 58102 (FAX: 701-234-2783).
    • ,
  • Michael A. Thomas, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Cincinnati Medical Center, Cincinnati, Ohio
    • ,
  • Daniel B. Williams, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, University of Cincinnati Medical Center, Cincinnati, Ohio
    • ,
  • Jared C. Robins, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Women and Infants Hospital, Brown University, Providence, Rhode Island

Received 14 November 2007; received in revised form 11 January 2008; accepted 14 January 2008. published online 17 July 2008.

Objective

To report on a patient with virilization during pregnancy who experienced delayed lactation secondary to elevated maternal androgens.

Design

Case report and review of the literature.

Setting

University hospital.

Patient(s)

A 32-year-old pregnant woman presented with virilization at 32 weeks' gestation.

Intervention(s)

Laboratory evaluation, ultrasound examination, magnetic resonance imaging, cesarean section for fetal indication, nipple stimulation to facilitate lactation.

Main Outcome Measure(s)

Case report.

Result(s)

Postpartum normalization of serum T levels and patient ability to breastfeed exclusively after delayed initiation of lactation.

Conclusion(s)

Maternal virilization during pregnancy is rare and is often due to androgen-secreting tumors that are benign. Therefore, careful evaluation of these patients is important to avoid inadvertent oophorectomy.

Key Words: Luteoma, pregnancy, tumor, virilization, musculinization, delayed breastfeeding

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PII: S0015-0282(08)00150-7

doi:10.1016/j.fertnstert.2008.01.055

Fertility and Sterility
Volume 90, Issue 5 , Pages 2006.e17-2006.e19, November 2008

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