Fertility and Sterility
Volume 91, Issue 5 , Pages 1877-1880 , May 2009

Ibuprofen and paracetamol for pain relief during medical abortion: a double-blind randomized controlled study

Received 1 November 2007 ,Revised 22 January 2008 ,Accepted 22 January 2008.

References 

  1. Fiala C, Gemzel-Danielsson K. Review of medical abortion using mifepristone in combination with a prostaglandin analogue. Contraception. 2006;74:66–86
  2. Weibe ER. Choosing between surgical abortions and medical abortion induced with methotrexate and misoprostol. Contraception. 1997;55:67–71
  3. Wiebe ER. Comparing abortion induced with methotrexate and misoprostol to methotrexate alone. Contraception. 1999;59:7–10
  4. Gemzell Danielsson K, Ostlund E. Termination of second trimester pregnancy with Mifepristone and gemeprost. The clinical experience of 197 consecutive cases. Acta Obstet Gynecol Scand. 2000;79:702–706
  5. Aschok PW, Templeton A, Wagaarachchi PT, Flett GM. Mid trimester medical termination of pregnancy: a review of 1002 consecutive cases. Contraception. 2004;69:51–58
  6. Hamoda H, Tempelton A. Analgesia requirements and predictors of analgesia use for women undergoing medical abortion up to 22 weeks of gestation. Br J Obstet Gynecol. 2004;111:996–1000
  7. Wiebe E. Pain control in medical abortion. Int J Gynaecol Obstet. 2001;74:275–280
  8. Creinin MD, Shulman T. Effect of non steroidal anti-inflammatory drugs on the action of misoprostol in a regimen for early abortion. Contraception. 1997;56:165–168
  9. Fiala C, Gemzell-Danielsson K. The effect of non steroidal anti-inflammatory drugs on medical abortions with mifepristone and misoprostol at 13-22 weeks of gestation. Hum Reprod. 2005;20:3072–3077
  10. American College of Obstetricians and Gynecologists . ACOG practice bulletin. Clinical management guidelines of obstetrician-gynecologists. Number 67, October 2005. Medical management of abortion. Obstet Gynecol. 2005;106:871–872
  11. Machtinger R, Seidman DS, Goldenberg M, Stockheim D, Schiff E, Shulman A. Transvaginal ultrasound and operative hysteroscopy in women undergoing medical termination of pregnancy as a part of routine follow-up. Fertil Steril. 2005;84:1536–1538
  12. Machtinger R, Seidman DS. Medical termination of pregnancy with mifepristone—initial experience at the Sheba Medical Center. Harefuah. 2003;142:666–668
  13. Abdel-Aziz E, Hassan I, Al-Taher HM. Assessment of pain associated with medical abortion. Int J Gynecol Obstet. 2004;84:264–265
  14. Li CF, Wong CY, Chan CP, Ho PC. A study of co-treatment of nonsteroidal anti-inflammatory drugs (NSAIDs) with misoprostol for cervical priming before suction termination of first trimester pregnancy. Contraception. 2003;67:101–105

 A.L. has nothing to disclose. R.M. has nothing to disclose. L.B.D. has nothing to disclose. M.S. has nothing to disclose. A.M.-Z. has nothing to disclose. D.S.S. has nothing to disclose.

PII: S0015-0282(08)00176-3

doi: 10.1016/j.fertnstert.2008.01.084

Fertility and Sterility
Volume 91, Issue 5 , Pages 1877-1880 , May 2009