Is there a limit for the number of in vitro fertilization cycles for an individual patient?
Received 7 February 2008; received in revised form 5 March 2008; accepted 5 March 2008. published online 12 May 2008.
To examine whether and when conception may be achieved in multiple repeated in vitro fertilization cycles, we surveyed the outcome of 2760 consecutive cycles in our unit. The pregnancy rate statistically significantly decreased after the third cycle attempt, but no statistically significant decrease was observed between cycles 4 and 20; an acceptable clinical pregnancy rate/cycle of 15% was achieved between cycles 7 and 20.
Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, and Ben Gurion University School of Medicine, Beer Sheva, Israel
Reprint requests: Raoul Orvieto, M.D., M.M.Sc., Director, Infertility and IVF Unit, Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon 78278, Israel (FAX: 972-8-6745134).
R.H. has nothing to disclose. S.M. has nothing to disclose. J.R. has nothing to disclose. S.S. has nothing to disclose. E.Y.A. has nothing to disclose. R.O. has nothing to disclose.
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