Fertility and Sterility
Volume 90, Issue 5 , Pages 2004.e7-2004.e9, November 2008

Persistent bilateral ureteral obstruction secondary to endometriosis despite treatment with an aromatase inhibitor

  • Justin Bohrer, B.S.

      Affiliations

    • Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio
  • ,
  • Chi Chiung Grace Chen, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio
    • Corresponding Author InformationCorrespondence to: Chi Chiung Grace Chen, M.D., Cleveland Clinic, 9500 Euclid Avenue, A81, Cleveland, Ohio 44195.
  • ,
  • Tommaso Falcone, M.D.

      Affiliations

    • Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio

Received 16 January 2008; received in revised form 14 March 2008; accepted 17 March 2008. published online 16 June 2008.

Objective

To present a case demonstrating lack of efficacy of an aromatase inhibitor in treating ureteral endometriosis.

Design

Case report.

Setting

A tertiary-care hospital.

Patient(s)

A 47-year-old woman with severe ureteral endometriosis.

Intervention(s)

Anastrozole 1 mg daily for 15 months.

Main Outcome Measure(s)

Renal function.

Result(s)

Despite medical management with anastrozole, our patient continued to have worsening renal function and subsequently required surgical intervention.

Conclusion(s)

Anastrozole was ineffective at preventing deterioration of renal function in this patient.

Key Words: Endometriosis, ureteral obstruction, anastrozole, aromatase inhibitor

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 J.B. has nothing to disclose. C.C.G.C. has nothing to disclose. T.F. has nothing to disclose.

 No reprints will be available.

PII: S0015-0282(08)00707-3

doi:10.1016/j.fertnstert.2008.03.040

Fertility and Sterility
Volume 90, Issue 5 , Pages 2004.e7-2004.e9, November 2008