GnRH agonist versus GnRH antagonist in controlled ovarian hyperstimulation: their role in patients with an unfavorable prognosis a priori
Received 8 February 2008; received in revised form 12 April 2008; accepted 12 April 2008. published online 04 August 2008.
In an attempt to examine the influence of the type of GnRH analogue used during controlled ovarian hyperstimulation on IVF outcome in patients with an unfavorable outcome a priori, we studied 728 consecutive cycles in patients with repeated IVF failure. In patients with repeated failure, the GnRH agonist group showed significantly higher clinical pregnancy rate compared with the GnRH antagonist group (20.8% vs 14.5%).
aDepartment of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel
bBenGurion University School of Medicine, Beer Sheva, Israel
Reprint requests: Professor Raoul Orvieto M.D., M.M.Sc., Director, Infertility and IVF Unit, Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon 78278, Israel (FAX: 972-8-6745134).
R.O. has nothing to disclose. R.H. has nothing to disclose. S.M. has nothing to disclose. J.R. has nothing to disclose. E.A. has nothing to disclose. S.S. has nothing to disclose.
ABSTRACT