Fertility and Sterility
Volume 91, Issue 4, Supplement , Pages 1424-1426, April 2009

Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia

  • Takahiro Haraguchi, M.D.
    • ,
  • Tomomoto Ishikawa, M.D., Ph.D.

      Affiliations

    • Corresponding Author InformationReprint requests: Tomomoto Ishikawa, M.D., Ph.D., Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-Cho, Chuo-Ku, Kobe 650-0017, Japan (FAX: 81-78-382-6169).
    • ,
  • Kohei Yamaguchi, M.D.
    • ,
  • Masato Fujisawa, M.D., Ph.D.

Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan

Received 21 January 2008; received in revised form 19 May 2008; accepted 20 May 2008. published online 11 August 2008.

The CCNA1, CCNB1, CCNB2, PRM1, and PRM2 messenger RNA transcript ratios were significantly decreased in patients with spermatogenic disorders. These messenger RNA transcript ratios in patients with successful sperm retrieval were higher than in patients with failed sperm retrieval.

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 T.H. has nothing to disclose. T.I. has nothing to disclose. K.Y. has nothing to disclose. M.F. has nothing to disclose.

PII: S0015-0282(08)01185-0

doi:10.1016/j.fertnstert.2008.05.072

Fertility and Sterility
Volume 91, Issue 4, Supplement , Pages 1424-1426, April 2009

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