Fertility and Sterility
Volume 92, Issue 3 , Pages 979-990, September 2009

Stimulation of spermatogenesis with recombinant human follicle-stimulating hormone (follitropin alfa; GONAL-f®): long-term treatment in azoospermic men with hypogonadotropic hypogonadism

  • Alvin M. Matsumoto, M.D.

      Affiliations

    • Department of Medicine, University of Washington School of Medicine, Seattle, Washington
    • Geriatric Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington
  • ,
  • Peter J. Snyder, M.D.

      Affiliations

    • University of Pennsylvania, Philadelphia, Pennsylvania
  • ,
  • Shalender Bhasin, M.D.

      Affiliations

    • Department of Medicine, Boston University, Boston, Massachusetts
    • Current address: Department of Endocrinology, Nutrition, and Diabetes, Boston, Medical Center, Boston, MA. Study patients were enrolled at Harbor-UCLA Medical Center, Torrance, CA.
  • ,
  • Kathryn Martin, M.D.

      Affiliations

    • Reproductive Endocrinology, Massachusetts General Hospital, Boston, Massachusetts
  • ,
  • Thomas Weber, M.D.

      Affiliations

    • Department of Medicine, Division of Endocrinology, Duke University Medical Center, Durham, North Carolina
  • ,
  • Stephen Winters, M.D.

      Affiliations

    • Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    • Current address: Division of Endocrinology, Metabolism and Diabetes, University of Louisville, KY.
  • ,
  • Daniel Spratt, M.D.

      Affiliations

    • Division of Reproductive Endocrinology and Infertility, Maine Medical Center and Maine Medical Center Research Institute, Portland, Maine
  • ,
  • Jim Brentzel, B.S.

      Affiliations

    • Clinical Development, EMD Serono, Inc., Rockland, Massachusetts
    • Corresponding Author InformationReprint requests: Jim Brentzel, B.S., EMD Serono, Inc., One Technology Place, Rockland, MA 02370 (FAX: 781-681-2901).
  • ,
  • Louis O'Dea, M.D.

      Affiliations

    • Radius Health, Inc., Cambridge, Massachusetts

Received 26 March 2008; received in revised form 23 June 2008; accepted 15 July 2008. published online 20 October 2008.

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 A.M.M. has received consultation fees and research funding from a number of pharmaceutical companies including GSK and Solvay Pharmaceuticals. P.J.S. has nothing to disclose. S.B. has received a research grant from Solvay Pharmaceuticals and study materials supplied by Auxilium. K.M. is the Senior Deputy Editor of a scientific journal. T.W. has nothing to disclose. S.W. has nothing to disclose. D.S. has nothing to disclose. J.B. is currently employed by EMD Serono, Inc. L.O. was previously employed by EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany.

 Supported by EMD Serono, Inc., Rockland, Massachusetts, USA.

PII: S0015-0282(08)03261-5

doi:10.1016/j.fertnstert.2008.07.1742

Fertility and Sterility
Volume 92, Issue 3 , Pages 979-990, September 2009